Padres vs Dodgers Prediction, Pick, Odds for Friday, August 15

Padres vs Dodgers Prediction, Pick, Odds for Friday, August 15 article feature image
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Photo Credit: Kirby Lee-Imagn Images. Pictured: Clayton Kershaw

The Los Angeles Dodgers host the San Diego Padres on August 15, 2025. First pitch from Dodger Stadium is scheduled for 10:10 p.m. EDT; the game will be broadcast on SportsNet LA.

Find my MLB betting preview and Padres vs Dodgers prediction below, as well as probable pitchers, betting trends, injury reports and more.

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My Padres vs Dodgers Prediction

  • Padres vs Dodgers picks: Dodgers First Five Innings -0.5 (-120) | Play to -133

My Padres vs Dodgers best bet is the Dodgers -0.5 in the first five innings. Make sure to find the best odds by checking our live MLB odds page.


Padres vs Dodgers Odds

Padres Logo
Friday, Aug 15
10:10 p.m. ET
MLB Network
Dodgers Logo
Padres Odds
SpreadTotalMoneyline
+1.5
-135
9
-120o / 100u
+145
Dodgers Odds
SpreadTotalMoneyline
-1.5
+115
9
-120o / 100u
-175
Odds via BetMGM. Get up-to-the-minute MLB odds here.
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Kenny Ducey’s Padres vs Dodgers Preview

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San Diego Padres Betting Preview

The Padres haven't announced a starter yet for Friday's tilt, and that could have everything to do with the fact that they'll likely be calling upon Randy Vasquez to work in a large role. As scary as that is, it appears it'll be their reality.

The right-hander was recently recalled from Triple-A after Michael King hit the IL again, and while his stay was brief it's not as if that's a good thing. He surrendered five earned runs on five hits and three walks over three frames in his only start, and that comes after months of relative ineffectiveness at the big-league level.

Yes, the righty has managed a tidy 3.93 ERA, but it's been largely due to the fact that he can pitch to fly balls quite well in his home park. Vasquez has surrendered a brutal 1.39 WHIP this season after posting a 1.51 WHIP last season, and that bundle of hits and walks is no surprise given his horrible .283 Expected Batting Average and career 8.9% walk rate.

The damage against him has also been palpable. He's come home with a .522 Expected Slugging that's even worse than his unsightly career marks. He's been bailed out by the spacious PETCO Park in big moments, but it's not as if his opponents have had a tough time reaching base.


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Los Angeles Dodgers Betting Preview

The Dodgers will go with a more known commodity here, and that's left-hander Clayton Kershaw. The veteran hasn't pitched like he did in his prime, but he's still finding ways to put his team in a winning position.

Kershaw's strikeout rate has come down to a minuscule 15.5% this year, and as his season has gone on, it's continued to get worse. What he's done, however, is do an excellent job of rolling up ground balls — and while his .267 xBA isn't the shiniest, it's still more or less average relative to pitchers like him.

The 37-year-old is likely going to encounter some turbulence when it comes to surrendering hits, but he's been rock steady when it comes to suppressing his opponents' power and he should be looked at as a reliable option here. He's allowed just one run on 12 hits over 12 frames this month, and he hasn't allowed a homer in five straight starts.


Padres vs Dodgers Prediction, Betting Analysis

As hot as the Padres' offense is right now, they hate to see a ground-ball pitcher coming. They're an offense tailored around contact with a low 15.1% strikeout rate over the past two weeks and a pedestrian .147 Isolated Power, but the magic has been in their consistency — and their ability to take a bunch of walks without sacrificing the low strikeout totals.

Kershaw has been brilliant at getting outs on contact, and ground-ballers are always a great bet against a team like the Padres.

On the flip side, the Dodgers have walked in over 11% of their plate appearances in the past two weeks, a huge deal when you consider their walk rate was down in the dumps just a few weeks ago.

With a beefier .178 ISO and a dream matchup against Vasquez, it's hard not to love the home team in a pivotal matchup in the division.

Pick: Dodgers First Five Innings -0.5 (-120) | Play to -133


Moneyline

I'm not betting the Padres vs Dodgers moneyline.


Run Line (Spread)

I'm going to bet the Dodgers to cover the run line in the first five innings.


Over/Under

I don't have a play for the Padres vs Dodgers over/under.


Padres vs Dodgers Betting Trends


Padres vs Dodgers Weather


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About the Author
Kenny Ducey, a leading voice in tennis betting and MLB handicapping, has built an online following through his work for Tennis Channel and his background in baseball reporting for Sports Illustrated and Baseball Prospectus. With over a decade of experience, including covering the New York Knicks and Yankees for Fordham's WFUV Radio, Ducey writes betting previews for Action Network and contributes digitally to Tennis Channel, having also worked for NBC Sports and DraftKings.

Follow Kenny Ducey @kennyducey on Twitter/X.

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