The Seattle Mariners host the San Diego Padres on May 17, 2026. First pitch from T-Mobile Park is scheduled for 7:20 p.m. ET. The game will be broadcast on Peacock.
The Mariners are favored by -162 on the moneyline and by -1.5 on the run line. The Padres are +136 on the moneyline and +1.5 on the run line. The total is set at 7.5 runs.
Find my MLB picks and Padres vs Mariners prediction below, as well as probable pitchers, weather report, and more.
Padres vs Mariners Prediction
- Padres vs Mariners Pick: Under 7.5 (-110)
My Padres vs Mariners best bet is Under 7.5 total runs in this game. Make sure to find the best odds by checking our live MLB odds page.
Padres vs Mariners Odds
| Padres Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -154 | 7.5 -110o / -110u | +136 |
| Mariners Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +128 | 7.5 -110o / -110u | -162 |
- Padres vs Mariners moneyline: Padres +136, Mariners -162
- Padres vs Mariners over/under: 7.5 (-110o / -110u)
- Padres vs Mariners spread: Padres +1.5 (-154), Mariners -1.5 (+128)
Padres vs Mariners Probable Pitchers
| RHP Lucas Giolito (SDP) -2025- | Stat | RHP George Kirby (SEA) |
|---|---|---|
| 10-4 | W-L | 5-2 |
| 2.0 | fWAR (FanGraphs) | 1.2 |
| 3.41 / 5.01 | ERA / xERA | 2.84 / 2.88 |
| 4.17 / 4.59 | FIP / xFIP | 3.24 / 3.53 |
| 10.6 | K-BB% | 14.1 |
| 37.8 | GB% | 57.0 |
| .273 | BABIP | .298 |
| 92 | Stuff+ | 100 |
| 101 | Location+ | 113 |
Padres vs Mariners MLB Betting Preview
San Diego Padres Betting Preview
The Padres (27-18) are looking to complete the sweep on the road against the Mariners. San Diego has now won five of its last eight games. The good news for them is their otherworldly closer, Mason Miller, didn't pitch in Saturday's win, so he's totally fresh for this matchup.
San Diego is sending out veteran right-hander Lucas Giolito, who is making his season debut after signing with the team late in the offseason. In Giolito's most recent rehab assignment at Double-A, he pitched six innings of one-run ball.
Facing an undermanned Mariners lineup that is playing without Cal Raleigh, we could see a quality outing from Giolito in this one.
Seattle Mariners Betting Preview
The Mariners (22-25) are looking to avoid the sweep at home vs. the Padres. Seattle has dropped three of its last four games, but they have a chance to get back on track with George Kirby on the mound.
The veteran right-hander has allowed two earned runs or fewer in six consecutive outings, so there's a good chance we see more of the same against the Padres.
What's also good news for the Mariners here is that Andres Munoz hasn't pitched in this series, so he's fully fresh.
Padres vs Mariners Pick, Betting Analysis
The Padres have a 72 wRC+ in the last seven days, which ranks 25th in MLB during that stretch. We could see Kirby shut down this underperforming offense, especially at home and in strong form, having allowed a combined 10 earned runs in his last six outings, spanning 37 innings.
Considering that Giolito looked sharp in his most recent rehab assignment at Double-A, coupled with the fact that this is at a pitcher's park, we could also see a quality outing from the veteran right-hander.
It also bodes well that the Mariners' bats have gone cold in this series, combining for just four runs in two games.
Then, add in the fact that both Mason Miller and Andres Munoz are fresh in this game, and you can see why the under looks appealing.
Pick: Under 7.5 (-110, FanDuel)
