The NBA regular season continues with a total of five matchups on the slate for this Friday. So, our staff of basketball betting experts dug into the latest odds and identified NBA best bets for all five of tonight's contests.
Continue below for our NBA best bets and predictions for Friday, February 27.
NBA Best Bets, Picks for Friday, February 27
| Game | Time (ET) | Pick |
|---|---|---|
  | 7 p.m. | |
  | 7:30 p.m. | |
  | 8 p.m. | |
  | 8:30 p.m. | |
  | 9:30 p.m. | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our NBA Odds page, which automatically surfaces the best lines for every game. | ||
Cavaliers vs. Pistons
By Matt Moore
The final injury report will determine the baseline competency of the Cavaliers’ offense in this game.
However, fully healthy, I make the total for this matchup 226 vs. the line of over/under 227.5.
If we assume an overall negative impact for the Cavs’ offense with Mitchell out and possibly Harden as well, then we have to lean toward the Under.
The absence of Mitchell and Harden should help the defense, even potentially without Schröder and Ellis.
There’s a potential game script where the Pistons smash the Cavaliers with their defense. There's also a world where the Cavs' offense grinds this game into the muck.
So, the Under has to be the play in tonight's contest.
Pick: Under 227.5 (-110)
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Nets vs. Celtics
Action PRO is projecting 8.31 rebounds for Neemias Queta in the Celtics' matchup against the Nets tonight, presenting a 10.2% edge against his current rebounds prop line of over/under 7.5, which is good enough to tag the Over with a B-grade in our database.
Queta has recorded 9+ rebounds in four straight games for the Celtics entering tonight, with three of those performances ringing in at 9+ rebounds.
The Nets play slow, ranking just 27th in pace. However, this should be a good spot for Queta to keep the momentum going against a Brooklyn squad that ranks 29th in offensive rating and 30th in points scored per game.
You could also consider climbing the ladder to 9+ Rebounds (+170) or 10+ Rebounds (+275) at DraftKings.
Pick: Neemias Queta Over 7.5 Rebounds (+105)
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Knicks vs. Bucks
By Matt Moore
The Knicks have been an Under team on the road, but Milwaukee is undersized, making it easier for Jalen Brunson to score.
Milwaukee has turnover issues, and the Knicks should dominate on the glass here, even if it’s a relative strength for the Bucks.
New York gives up a high number of threes (bottom-10 allowed), and the Bucks are 10th in 3-point rate and 2nd in percentage.
They’ll fire from deep, and should make enough to push this game Over the number.
Pick: Over 220.5 (-110)
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Grizzlies vs. Mavericks
By Joe Dellera
The Grizzlies face off against the Mavericks tonight — and these teams are both fully in on the youth movement at this point, so we should expect to see the young guns at the helm today.
For Memphis, Ty Jerome is doubtful, and even though he’s been playing just 20 minutes per game, his usage rate has been massive, so removing him opens up a lot of opportunities for others.
GG Jackson has been great for Memphis whenever he gets extended run, and he’s consistently seen minutes in the mid-to-upper 20s since the break.
Over his last five games, Jackson is averaging 26.8 minutes and 21.8 points per game.
Now, he gets a spot against the Mavericks who are very weak in the paint and at the rim — two spots where he thrives.
I’ll back GG in this spot against the Mavericks tonight.
Pick: GG Jackson Over 15.5 Points (-125)
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Nuggets vs. Thunder
By Bet Labs
This NBA spread betting system identifies value in large favorites that the public tends to fade such as the Thunder in this spot.
It focuses on regular or postseason games where the favorite opens with a significant spread yet receives limited betting support, often below 40%.
These are spots where the market overreacts to recent performances, particularly when the opponent is coming off a strong win by a large margin.
Public bettors often chase momentum and undervalue elite teams laying points, assuming the line is inflated.
Historically, these contrarian favorites outperform expectations as sharp money backs the undervalued side while casual bettors load up on the underdog.
This system exploits those perception gaps, capitalizing on strong teams that are capable of covering despite public skepticism.
Pick: Thunder -8 (-115)
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