The Drake Bulldogs take on the LSU Tigers in Destin, FL, in the Emerald Coast Classic. Tip-off is set for approximately 9:30 p.m. ET on CBS Sports Network.
LSU is favored by -12 points on the spread with a moneyline of -950. The total is set at 151 points.
Here’s my Drake vs. LSU predictions and college basketball picks for November 28, 2025.
Drake vs LSU Prediction
My Pick: Drake +12
My Drake vs LSU best bet is on the Bulldogs to cover the spread. For all of your college basketball bets, be sure to find the best lines by using our live NCAAB odds page.
Drake vs. LSU Odds
| Drake Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+12 -110 | 151 -110o / -120u | +625 |
| LSU Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-12 -110 | 151 -110o / -120u | -950 |
- Drake vs LSU spread: LSU -12
- Drake vs LSU over/under: 151 points
- Drake vs LSU moneyline: Drake +625, LSU -950
Drake vs LSU College Basketball Betting Preview
Drake is still adjusting to life under new head coach Eric Henderson, as it has losses to Robert Morris (180th in KenPom) and SIU Edwardsville (200th).
The Bulldogs now step up in weight class as they take on LSU on Friday in the Emerald Coast Classic.
The Tigers haven't exactly played a murderer's row of opponents (no power-conference matchups yet), but they're 5-0 with every win coming by at least 17 points.
While this write-up seems to be trending towards LSU, the play for this game is actually on the underdog — Drake — to cover the spread.
That's according to our very own Evan Abrams, who has a system called "Bad ATS over Good ATS, High Total" that's eyeing the Bulldogs ATS.
In early-season college basketball, games featuring high totals and mismatched teams against the spread often create value on the underperforming side.
When one team has struggled to cover while its opponent has consistently exceeded expectations, public sentiment tends to favor the team with the stronger record against the number.
However, in fast-paced, high-total environments, volatility increases and closing margins tighten.
Poor ATS teams are often priced at their lowest point, while efficient teams are overvalued following strong runs.
Early in the season, with limited data and defensive structures still forming, these matchups frequently swing back toward balance, allowing the undervalued side to outperform inflated lines and cover at a profitable rate.
Also, while this system is just 31-33 this season, it has a 5% return on investment (ROI) historically, making it a reliable system to target for picks.
My Pick: Drake +12
