The Portland State Vikings take on the Stanford Cardinal in Stanford, CA. Tip-off is set for 10 p.m. ET on ACC Network Extra.
Stanford is favored by -10.5 points on the spread with a moneyline of -605. The total is set at 143.5 points.
Here’s my Portland State vs. Stanford predictions and college basketball picks for November 5, 2025.
Portland State vs Stanford Prediction
My Pick: Stanford -10.5
My Portland State vs Stanford best bet is on the Cardinal spread. For all of your college basketball bets, be sure to find the best lines by using our live NCAAB odds page.
Portland State vs. Stanford Odds
| Portland State Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+10.5 -110 | 143.5 -110o / -110u | +475 |
| Stanford Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-10.5 -111 | 143.5 -110o / -110u | -650 |
- Portland State vs Stanford spread: Stanford -10.5
- Portland State vs Stanford over/under: 143.5 points
- Portland State vs Stanford moneyline: Portland State +475, Stanford -650
Portland State vs Stanford College Basketball Betting Preview
The “Opening Home Favs (V1)” system targets opening home favorites in college basketball, focusing on teams playing their very first game of the season. These teams are at home, entering with a clean slate, and often coming off a previous year with fewer than 20 wins.
The idea is that early in the season, oddsmakers may undervalue these programs, especially against opponents with more preseason buzz or established reputations. Playing at home provides a comfort advantage, and being listed as a favorite or pick implies early market confidence despite modest prior results.
With totals capped at 149.5, this typically captures games expected to be moderately paced rather than high-scoring shootouts. Historically, these home teams tend to outperform the spread as they aim to set the tone for a bounce-back season and reward early bettors backing them in their opener.
Overall, the system stands at 607-524-22 (54%) with a 4% return on investment (ROI) across all-time results, and it’s off to a 14-11-0 (56%) start this season with an 8% ROI.
My Pick: Stanford -10.5
