Owls vs. 49ers Odds & Betting Predictions - September 18, 2025
Owls at 49ers
11:30 pm • ESPNOwls at 49ers Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Owls 5-8 | -6.5 | -1.5-110 | o42.5-110 | -122 |
49ers 1-11 | u45.5 | +1.5-110 | u42.5-110 | +102 |

Jerry Richardson StadiumCharlotte
Owls vs. 49ers Expert Picks
Boomer Betz
Last 30d: 82-108-0 (-50.9u)
Under 42.5 (Live)+113
1u
Austin Pendergrass
Last 30d: 32-34-0 (-5.7u)
RICE -122
0.41u
YBK Picks.com
Last 30d: 21-16-0 (+9.6u)
CHA +2.5-105
3u
Dan Gaspar
Last 30d: 0-0-0 (+0.0u)
C.Stokes o26.5 Rush Yds-114
1.14u
Scott Rickenbach
Last 30d: 110-107-2 (-12.7u)
Under 42.5-110
1u
💰🦡 Jake
Last 30d: 84-101-4 (+6.9u)
Under 20.5 (1H)-108
1.08u
Duck
Last 30d: 82-71-0 (+0.2u)
RICE -125
0.3u
Fun bet. Think rice can create some advantages in the run game here against the Charlotte DL. Charlotte offensive performance last week was all about Monmouth, not about 49ers. Fun game. Small bet.
Road to CFB
Last 30d: 3-4-0 (-0.5u)
RICE o10.5 Team Total (1H)+105
1u
Collin Wilson
Last 30d: 9-9-3 (-0.3u)
Under 45.5-105
0.5u
Project 41; both offenses super slow. Rice over 30 seconds per play and a heavy 83% rush play calling. Rice D has been fantastic in standard downs success rate
Owls vs. 49ers Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Owls vs. 49ers Public Betting Percentages
Betting Trends
- 49ers are 1-4 in their last 5 games.
- 49ers are 1-4 in their last 5 games against the spread
- 49ers are 4-1 in their road games against the spread
- The totals have gone OVER in 3 of 49ers' last 5 games
- The totals have gone OVER in 4 of 49ers' 6 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Team Stats
98
YDS
259
9/12
Comps/Atts
23/44
8.166666666666666
YPA
5.886363636363637
1/0
TDs/INTs
1/0
0/0
Sacks/Yards
6/45
Owls vs. 49ers Odds Comparison
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Owls at 49ers Team Totals
MatchupOverUnder | ||
|---|---|---|
Owls 5-8 | N/A | N/A |
49ers 1-11 | N/A | N/A |






