Week 4 College Football Straight-Up Picks: A Slate of Sneaky Home Dogs

Week 4 College Football Straight-Up Picks: A Slate of Sneaky Home Dogs article feature image

USA TODAY Sports. Pictured: AJ Dillon, Alex Hornibrook and Kylin Hill

  • Our college football experts have picked 10 of the biggest games of Week 4, straight-up.
  • League play is starting to ramp up, so a lot of these games will have an impact on those conference landscapes.

Last week, there was chaos in college football. There were four straight-up upsets of greater than 4-1, underdogs were 37-27-2 against the spread and two College Football Playoff contenders went down.

Will we get more of the same in Week 4? Our experts don’t think so.

Our nine-person panel this week includes: Ken Barkley, Matt Moscona, Steve Petrella, Brad Senkiw, Stuckey, Josh Ward, Brad Kellner, Lauren Joffe and Collin Wilson.

The panel will make selections for 10 of the week’s most intriguing matchups. Games with massive point spreads (sorry, Alabama) have intentionally been excluded.

Remember, these are straight-up picks, not against the spread.

Week 4 College Football Picks

>> All odds as of 12 a.m. ET on Friday. Download The Action Network App to get real-time odds and track your bets.

Boston College (-6.5) at Purdue 

Boston College (7): Petrella, Barkley, Moscona, Wilson, Ward, Joffe, Senkiw

Purdue (2): Stuckey, Kellner

Boston College is sneaking into the ACC conversation thanks to a stout running game, led by AJ Dillon.

Stanford (-2) at Oregon

Stanford (2): Barkley, Kellner

Oregon (7): Petrella, Stuckey, Moscona, Wilson, Ward, Joffe, Senkiw

Stanford has dismantled Oregon each of the last two years, by a combined score of 101-34.

Florida (-4.5) at Tennessee

Florida (7): Barkley, Kellner, Moscona, Wilson, Ward, Joffe, Senkiw

Tennessee (2): Stuckey, Petrella

The Gators are reeling from a loss to Kentucky, Florida’s first in the series in three decades (though the Gators did bounce back with a win over Colorado State last weekend), while the Vols stumbled through nonconference play against inferior competition (minus West Virginia, which trounced Tennessee in Week 1).

Nebraska at Michigan (-18.5)

Nebraska (0): None

Michigan (9): Stuckey, Petrella, Barkley, Kellner, Moscona, Wilson, Ward, Joffe, Senkiaw

Jim Harbaugh has been excellent in Big Ten openers, and Nebraska may be without its quarterback.

TCU (-3.5) at Texas

TCU (6): Petrella, Barkley, Kellner, Ward, Joffe, Senkiw

Texas (3): Stuckey, Moscona, Wilson

Texas knocked off USC last week, while TCU played a really competitive game against Ohio State.

Wisconsin (-3) at Iowa

Wisconsin (8): Petrella, Stuckey, Kellner, Moscona, Wilson, Ward, Joffe, Senkiw

Iowa (1): Barkley

The public is down on Wisconsin after it lost to BYU last week, but our staff isn’t.

Notre Dame (-7.5) at Wake Forest

Notre Dame (9): Petrella, Stuckey, Barkley, Kellner, Moscona, Wilson, Ward, Joffe, Senkiw

Wake Forest (0): None

There might be a quarterback change for Notre Dame, since Brandon Wimbush hasn’t looked comfortable passing in any of the Irish’s first three games.

Mississippi State (-9.5) at Kentucky

Mississippi State (8): Petrella, Stuckey, Barkley, Kellner, Moscona, Wilson, Ward, Senkiw

Kentucky (1): Joffe

Mississippi State has plowed through the early part of its schedule and begins SEC play with a tricky test in Lexington against a confident Kentucky team.

Georgia (-14.5) at Missouri

Georgia (9): Petrella, Stuckey, Barkley, Kellner, Moscona, Wilson, Ward, Joffe, Senkiw

Missouri (0): None

Georgia’s offense hasn’t kicked it into high gear yet — it’s limiting the carries of star running back D’Andre Swift — but it might need to against Drew Lock and Mizzou’s potent passing attack.

South Carolina (-2.5) at Vanderbilt

South Carolina (6): Barkley, Kellner, Moscona, Ward, Joffe, Senkiw

Vanderbilt (3): Petrella, Stuckey, Wilson

Vandy is 3-0 against the spread this season, covering by an average of 18.3 points.