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The Old Dominion Monarchs take on the Louisiana Tech Bulldogs in Ruston, LA. Kickoff is set for 5 p.m. ET on ESPN+.
Louisiana Tech is favored by -12.5 points on the spread with a moneyline of -490. The total is set at 45.5 points.
Here’s my Old Dominion vs. Louisiana Tech prediction and college football pick for Saturday, October 24, 2026.
Old Dominion vs Louisiana Tech Prediction
- Old Dominion vs. Louisiana Tech Pick: Old Dominion +13.5
My Louisiana Tech vs. Old Dominion best bet is on the Monarchs to cover the spread. Find the best line available on our live NCAAF odds page.
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Old Dominion vs Louisiana Tech Odds
| Old Dominion Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+12.5 -110 | 45.5 -118o / -112u | +365 |
| Louisiana Tech Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-12.5 -110 | 45.5 -118o / -112u | -490 |
- Old Dominion vs Louisiana Tech point spread: Louisiana Tech -12.5 (-110), Old Dominion +12.5 (-110)
- Old Dominion vs Louisiana Tech over/under: 45.5 (-118o / -112u)
- Old Dominion vs Louisiana Tech moneyline: Old Dominion +365, Louisiana Tech -490

Old Dominion vs Louisiana Tech Pick, Betting Analysis
At 4-2, Louisiana Tech looks to continue its early-season success against 2-5 Old Dominion.
The Bulldogs have won three straight games, with their own two losses coming on the road against Baylor and LSU.
So, shouldn't we be backing the Bulldogs to maul the Monarchs?
Not according to Evan Abrams' Bet Labs Sports Insight system — "Early Road Redemption" — which says that the Monarchs against the spread is the play.
This system has a 9% return on investment (ROI) all-time, making it reliable and consistent over a period of time.
Early Road Redemption is a college football system that identifies value on visiting teams in the opening stretch of the season after they have underperformed against the spread in their previous outing.
The market often punishes these teams too heavily for a single early loss, creating inflated lines in the next matchup.
By narrowing the spread range between modest underdogs and double digit spots, the system captures situations where the road team is competitive but overlooked.
These games are played in manageable weather conditions and typically fall within lower scoring totals, which reduce volatility and keep contests closer than expected.
When teams in their first eight games seek redemption on the road after a poor showing against the spread, they frequently outperform expectations, making this a profitable angle.
Pick: Old Dominion +13.5


















