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Wake Forest vs Virginia Tech Prediction, Pick, NCAAF Odds for Saturday, October 4

Wake Forest vs Virginia Tech Prediction, Pick, NCAAF Odds for Saturday, October 4 article feature image
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Zachary Taft-Imagn Images. Pictured: Jake Dickert (Wake Forest)

The Wake Forest Demon Deacons take on the Virginia Tech Hokies in Blacksburg, VA. Kickoff is set for 1 p.m. ET on The CW.

Virginia Tech is favored by -7 points on the spread with a moneyline of -260. The total is set at 50.5 points.

Here’s my Wake Forest vs. Virginia Tech predictions and college football picks for Saturday, October 4, 2025.

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Wake Forest vs Virginia Tech Prediction

  • Wake Forest vs. Virginia Tech Pick: Wake Forest ML +215

My Virginia Tech vs. Wake Forest best bet is on the Demon Deacons moneyline. Find the best line available on our live NCAAF odds page.


Wake Forest vs Virginia Tech Odds

Wake Forest Logo
Saturday, October 4
1 p.m. ET
The CW
Virginia Tech Logo
Wake Forest Odds
SpreadTotalMoneyline
+7
-115
50.5
-112o / -108u
+210
Virginia Tech Odds
SpreadTotalMoneyline
-7
-105
50.5
-112o / -108u
-260
Odds via bet365. Get up-to-the-minute NCAAF odds here.
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  • Wake Forest vs Virginia Tech point spread: Virginia Tech -7
  • Wake Forest vs Virginia Tech over/under: 50.5 points
  • Wake Forest vs Virginia Tech moneyline: Wake Forest +210, Virginia Tech -260
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Wake Forest vs Virginia Tech Pick, Betting Analysis

Virginia Tech enters this ACC clash on a two-game winning streak, with one of the victories coming in its first league game of the season against NC State.

Meanwhile, on the flip side, Wake Forest enters on a two-game losing streak, including losses at home to No. 16 Georgia Tech in overtime and NC State.

Now the Demon Deacons are heading on the road looking to wake up from the bottom of the ACC standings.

Will they notch their first conference victory of the season? Our very own Evan Abrams has a system called "Normal Rest Contrarian Dogs" that thinks they will win straight up on the moneyline.

In fact, this system has a 7% return on investment (ROI) overall and a 31% ROI this season alone.

In college football, normal rest contrarian 'dogs are teams that have had a full week or slightly longer to prepare, yet still face significant betting line movement against them.

When the spread shifts multiple points from open to close, it often signals strong market confidence in the favorite. However, these 'dogs, playing in the heart of the season from September through November or into the postseason, benefit from preparation time and game planning.

With spreads in the moderate to large range, they're capable of upsetting inflated odds, especially when the market’s perception has tilted too far, creating hidden value on the moneyline.

Take the Deacs with nice value on the moneyline.

Pick: Wake Forest ML +215



Wake Forest vs Virginia Tech Betting Trends



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