Broncos vs. 49ers Odds & Betting Predictions - August 10, 2025
Broncos at 49ers
12:30 am • NFL+Broncos at 49ers Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Broncos 4-2 | -6.5-109 | o38.5-109 | -280 | |
49ers 6-0 | +6.5-111 | u38.5-110 | +240 | |

Levi's StadiumSanta Clara
Broncos vs. 49ers Previews & Analysis
Broncos vs. 49ers Props
Prop Projections
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Prop Odds Comparison
Line Movement Tracker
Broncos vs. 49ers Public Betting Percentages
Betting Trends
- 49ers are 5-0 in their last 5 games.
- 49ers are 3-2 in their last 5 games against the spread
- 49ers are 1-0 in their road games against the spread
- The totals have gone OVER in 2 of 49ers' last 5 games
- The totals have gone OVER in 2 of 49ers' 4 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Broncos vs. 49ers Injury Updates

Broncos Injuries
- Tyler BadieRB
Badie is questionable with thumb
Questionable
- Pat BryantWR
Bryant is out with ankle
Out
- Jonah ColemanRB
Coleman is out with ankle
Out

49ers Injuries
- Mike EvansWR
Evans is out with achilles
Out
- Demarcus RobinsonWR
Robinson is out with ankle
Out
- Christian KirkWR
Kirk is questionable with calf
Questionable
- Deebo SamuelWR
Samuel is out with hamstring
Out
- Jake TongesTE
Tonges is out with knee
Out
- De'Zhaun StriblingWR
Stribling is out with ankle
Out
Team Stats
Broncos vs. 49ers Odds Comparison
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Broncos at 49ers Team Totals
MatchupOverUnder | ||
|---|---|---|
Broncos 4-2 | N/A | N/A |
49ers 6-0 | N/A | N/A |

