Dolphins vs. Bills Odds & Betting Predictions - November 22, 2026

Dolphins at Bills

6:00 pm • CBS
@

Dolphins at Bills Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Dolphins
1-6
N/A
N/A
N/A
Bills
6-1
N/A
N/A
N/A
location pinSunday 6:00 p.m.
November 22, 2026
Highmark StadiumOrchard Park

Dolphins vs. Bills Props

Prop Projections

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Dolphins vs. Bills Public Betting Percentages

Away Logo

Dolphins

Public

50%

Bets%

50%

Money%

NFL Public Betting Right Arrow

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Bills
5-23-12-14-21-0
Dolphins
3-3-11-1-12-2N/A3-3-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Bills
5-22-23-04-21-0
Dolphins
4-32-12-2N/A4-3

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Bills
6-1N/AN/A5-11-0
Dolphins
1-6N/AN/AN/A1-6

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Nov 1stBALW 36-10-3 WU 55BUF -175
Oct 18th@LVW 33-30-5.5 LO 54.5BUF -235
Oct 13th@LAW 37-34+3.5 WO 55.5BUF +150
Oct 4thNEL 26-29-7 LO 49.5NE -350
Sep 27thLACW 24-16-7.5 WU 50.5BUF -350

Bills vs. Dolphins Injury Updates

Bills Injuries

  • Joshua Palmer
    WR

    Palmer is out with hamstring

    Out

Dolphins Injuries

  • De'Von Achane
    RB

    Achane is out with knee

    Out

  • Jaylen Wright
    RB

    Wright is out with quad

    Out

Player Stats
  • passing yards
    Josh Allen logo
    Josh Allen
    1793
    pyds
  • passing touchdowns
    Josh Allen logo
    Josh Allen
    11
    ptd
  • rushing yards
    James Cook logo
    James Cook
    707
    ryds
  • rushing touchdowns
    Josh Allen logo
    Josh Allen
    9
    rtd
Depth Charts
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Starter2ND3RD4TH
QBJosh AllenKyle AllenShane Buechele
RBJames CookTy JohnsonRay DavisFrank Gore
WRKhalil ShakirStephen Gosnell
TEDalton KincaidDawson KnoxJackson HawesKeleki Latu
LTDion DawkinsJude BowryChase Lundt
LGAlec AndersonAustin Corbett
CConnor McGovernLloyd Cushenberry
RGO'Cyrus TorrenceAr'maj Reed-Adams
RTSpencer BrownTylan Grable
LDET.J. SandersLandon Jackson
WLBDorian WilliamsKaleb Elarms-Orr
MLBTerrel BernardKeonta JenkinsJoe Andreessen
LCBChristian BenfordDavison Igbinosun
SSDamar HamlinJalon Kilgore
FSCole BishopGeno StoneSam Franklin
RCBMaxwell HairstonKani Walker
PTommy Doman
HTommy Doman
PRKhalil ShakirKeon ColemanSkyler Bell
KRRay DavisTy JohnsonSkyler Bell
LSReid Ferguson
LWRKeon ColemanJoshua PalmerTrent Sherfield
LOLBGreg RousseauMichael HoechtMike Danna
DTEd OliverZane Durant
ROLBBradley ChubbTJ ParkerJavon SolomonAndre Jones
NTDeone Walker
RWRDJ MooreSkyler BellJa'Mori Maclin
NBDee AlfordJordan HancockTe'Cory Couch
KTyler Bass
Team Stats
1167
YDS
1713
108/183
Comps/Atts
135/205
6.929
YPA
8.746
6/5
TDs/INTs
11/5
21/101
Sacks/Yards
13/80
863
Rush Yards
1039
194
Attempts
217
4.448
YPC
4.788
7
TDs
16

Turnovers

Fumbles Lost
5
Interceptions
5

Efficiency

10/18 55.56%
Redzone
21/30 70%
38/89 0%
3rd Down
34/77 0%
5/10 0%
4th Down
7/9 0%

First Downs

117
Total
167
56
Pass
79
49
Rush
68
12
Penalty
20
/
Penalties/Yards
/
Possession

Dolphins vs. Bills Odds Comparison

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Dolphins at Bills Team Totals

MatchupOverUnder
Dolphins
1-6
N/A
N/A
Bills
6-1
N/A
N/A