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Monday Night Football offers an exciting clash between two 6-1 teams, but things aren't all that similar beyond their season records.
The Minnesota Vikings are coming off their first loss against the Lions, and QB Kyler Murray has been ruled out for this matchup, while the Buffalo Bills are on a three-game winning streak.
Then, you have to look at their very contrasting styles, which will definitely impact how you bet this MNF, so let's get right to it.
We'll start with two active signals on our NFL Sharp Report for Bills vs. Vikings on Monday.
2 Smart O/U Picks for Bills vs. Vikings
With Murray's hamstring injury keeping him on the sidelines for Monday Night Football, Carson Wentz will be the starting quarterback against the Bills.
Wentz hasn't played a snap since September, after taking the field against the Packers and Bears. Even with Murray's performance being questioned, this forced change at QB has made the Bills a 3-point and moneyline road favorite here.
However, our PRO Report
