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Arizona Cardinals vs NY Giants Predictions, Picks, Week 4 Odds

Arizona Cardinals vs NY Giants Predictions, Picks, Week 4 Odds article feature image
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Reuters Connect/Imagn. Pictured: Jacoby Brissett, Malik Nabers.

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The Arizona Cardinals (1-2) and New York Giants (2-1) meet today in NFL Week 4. Kickoff is set for 1 p.m. ET from MetLife Stadium in East Rutherford, N.J. The game will broadcast live on CBS.

The Cardinals are 2.5-point favorites over the Giants on the spread (Cardinals -2.5), with the over/under set at 44.5 (-105o / -115u). Arizona is a -137 moneyline favorite to win and New York is a +116 underdog..

Let's get into my Cardinals vs Giants predictions for Sunday, October 4.


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Cardinals vs Giants Predictions, Pick

My Cardinals vs. Giants best bet is the total to go Over 43.5 points, with the best price currently available at FanDuel. Make sure to find the best odds by checking our live NFL odds page.

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Cardinals vs Giants Odds

Cardinals Logo
Sunday, Oct. 4
1 p.m. ET
CBS
Giants Logo
Cardinals Odds
SpreadTotalMoneyline
-2.5
-110
44.5
-105o / -115u
-137
Giants Odds
SpreadTotalMoneyline
+2.5
-109
44.5
-105o / -115u
+116
Odds via Caesars. Get up-to-the-minute NFL odds here.
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Cardinals vs Giants Week 4 Preview: Jacoby vs. Jameis

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Cardinals Preview: Surprisingly Competent Offense

The Cardinals' offense has played crisp, efficient football behind Jacoby Brissett.

Brissett provides a high floor of competency, distributing the ball effectively to Arizona's dynamic skill players. He routinely peppers star tight end Trey McBride, who has 33 targets through three games.

Rookie running back Jeremiyah Love is also coming off the best game of his young career after he rushed for 90 yards and scored a receiving touchdown against the 49ers.

The Cardinals shouldn't have much trouble moving the ball against a heavily compromised New York defensive unit.


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Giants Preview: The Jameis Winston Experience

The Giants' season was thrown into chaos when Jaxson Dart went down, forcing Jameis Winston into the starting lineup.

The Jameis experience typically leads to high-variance fireworks; he loves to aggressively push the ball downfield and force tight-window throws. He played things pretty conservatively in the rain last week against Tennessee, but the Giants likely won't be able to tame the beast two weeks in a row.

To make matters worse, Giants edge rusher Brian Burns is out, leaving a pass rush that generated just three pressures on Cam Ward last week completely neutered.


Cardinals vs Giants Pick to Make

Sharps out here in Vegas are already betting this Over, causing the line to cross key numbers.

Without Brian Burns generating pressure, Jacoby Brissett should be able to sit comfortably in the pocket and pick apart a banged-up Giants secondary.

Meanwhile, Jameis Winston will likely push the pace and sling it downfield for the Giants. Expect a fast-paced, high-scoring shootout.

Pick: Over 43.5 (-118)


Cardinals vs Giants Trends for Week 4

Cardinals Trends

  • The Cardinals are 6-1 ATS against the NFC East over the last five seasons.

Giants Trends

  • Jameis Winston is 17-6 to the Over in October in his career (since 2015).
  • Jacoby Brissett and Jameis Winston have faced off just once in their careers. The O/U was 46.5 and the Colts and Bucs combined for 72 points that day.

Cardinals vs Giants Viewing Info: Channel, Start Time, Streaming

Location:MetLife Stadium
Date:Sunday, Oct. 4
Time:1:00 p.m. ET
TV / Streaming Options:FOX

Cardinals vs Giants Weather

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