Eagles vs. Bills Betting Odds, Picks & Predictions

Eagles vs. Bills Betting Odds, Picks & Predictions article feature image
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Bill Streicher-USA TODAY Sports. Pictured: Carson Wentz

  • We cover every actionable angle of the Philadelphia Eagles at Buffalo Bills.
  • Find betting odds, our experts' picks, projections and more below.

Eagles at Bills Odds, Picks & Predictions

  • Odds: Bills -2
  • Over/Under: 40
  • Kickoff: 1 p.m. ET
  • TV Channel: FOX

Odds as of Sunday morning and via PointsBet, where Action Network users can access an exclusive promotion to get a 200% deposit match (deposit $50, bet with $150).


Our analysts and experts break down the most important angles of this game.

Here's an excerpt, but you can read the full story here.

The Bills are 5-1 with their one loss coming at home to New England, but the five teams they’ve beat have a combined 6-27 record. They won those games by a combined 36 points — a little more than a touchdown per game.

That would be bad enough, but the five quarterbacks they beat have three (!) combined wins and two of them (Marcus Mariota and Eli Manning) are now backups riding the pine.

See our full betting breakdown for Eagles-Bills.

Our Experts' Favorite Week 8 Picks

Our staff breaks down how they're betting 1 and 4 p.m. ET games. See their picks.

Sean Koerner's Projected Eagles-Bills Odds

Sean Koerner uses his NFL Power Ratings to project a spread and total for every game. See whether he thinks either are worth a bet in this matchup.

Pick 'Em Confidence Rating

Sean Koerner ranks every straight-up and against-the-spread pick for pools in his Pick 'Em Confidence Ratings. You can even create custom ATS ratings based on the specific spreads your league is using.

See where the Eagles and Bills rank.

Survivor Pool Recommendations

Seven weeks down. Ten to go. Should you roll with Philly or Buffalo in Week 8? Our NFL simulations reveal the best survivor pool picks.

Week 8 Fantasy Football Rankings

Our trio of experts are obsessively updating their fantasy football rankings so you can set your lineups with confidence. Here's how they rank QBs, RBs, WRs, TEs and Flex players for PPR, standard and half PPR leagues.

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