Panthers vs. Patriots NFL Odds, Pick & Prediction: How Wiseguys Are Betting Friday Night’s Preseason Matchup

Panthers vs. Patriots NFL Odds, Pick & Prediction: How Wiseguys Are Betting Friday Night’s Preseason Matchup article feature image
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Photo by Maddie Meyer/Getty Images. Pictured: Head coach Bill Belichick of the New England Patriots

Panthers vs. Patriots Odds

Panthers Odds+4.5
PatriotsOdds-4.5
Over/Under40
DateFriday, Aug. 19
Time7 p.m. ET
ChannelNFL Network

*Odds as of Friday morning

Week 2 of the 2022 NFL preseason rolls on with a three-game slate on Friday night, beginning with Panthers vs. Patriots at 7 p.m. ET.

So far this preseason, we've seen lots of early odds movement as the market adjusts to player news, then an influx of smart money on the morning of games as wiseguys take their betting positions.

Tonight's Panthers vs. Patriots matchup is a perfect example as respected bettors swiftly got down on one side of this game, forcing a market-wide adjustment adjustment from oddsmakers in reaction.

Using our NFL betting picks and predictions, let's examine the sharp side of Panthers vs. Patriots on Friday night.

Panthers vs. Patriots Pick