Oilers vs. Senators Odds & Betting Predictions - October 21, 2025

Oilers at Senators

11:00 pm • ESPN+

Edmonton Oilers

@

Ottawa Senators

MatchupOpenSpreadTotalMoneyline
Oilers 2-3-1	-1.5	-1.5+170	o6-105	-141
Senators 2-4-0	u5.5	+1.5-205	u6-112	+119

location pin

Tuesday 11:00 p.m.

October 21, 2025

Canadian Tire CentreOttawa

No props found

NHL Public Betting

Senators are 2-3 in their last 5 games.
Senators are 1-4 in their last 5 games against the spread
Senators are 1-2 in their road games against the spread
The totals have gone OVER in 4 of Senators' last 5 games
The totals have gone OVER in 2 of Senators' 3 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Senators	1-5	0-3	1-2	0-4	1-1
Oilers	2-4	1-1	1-3	2-4	N/A

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Senators	5-1	2-1	3-0	3-1	2-0
Oilers	3-3	1-1	2-2	3-3	N/A

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Senators	2-4	N/A	N/A	1-3	1-1
Oilers	2-3	N/A	N/A	2-4	N/A

date	opponent	score	spread	over/under	moneyline
Oct 18th	NYI	L 4-5	-1.5 L	O 5.5	NYI -134
Oct 16th	SEA	W 4-3	-1.5 L	O 6	OTT -158
Oct 15th	@BUF	L 4-8	-1.5 L	O 6.5	BUF -112
Oct 13th	NSH	L 1-4	-1.5 L	U 5.5	NSH -175
Oct 11th	@FLA	L 2-6	+1.5 L	O 5.5	FLA +130

Mattias Janmark
C
Janmark is out with undisclosed
Out
Zach Hyman
LW
Hyman is out with wrist
Out
Kasperi Kapanen
RW
Kapanen is day-to-day with undisclosed
Day-to-Day
Stuart Skinner
G
Skinner is injured with upper body
Out Indefinitely
Alec Regula
D
Regula is out with undisclosed
Out

Brady Tkachuk
LW
Tkachuk is out with thumb
Out

See more NHL Injuries

2.6

Goals

3.17

2.2

Goals Against

4.5

3.6

Penalties

4.67

31.4

Shots

31.17

16.8

Hits

27

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MatchupOverUnder
Oilers 2-3-1	N/A	N/A
Senators 2-4-0	N/A	N/A