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PSV vs Liverpool Prediction, Picks, Odds for Champions League Matchday 5

PSV vs Liverpool Prediction, Picks, Odds for Champions League Matchday 5 article feature image
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Pictured: Mohamed Salah. (Photo by James Gill – Danehouse/Getty Images)

PSV Eindhoven (1-1-2) and Liverpool (3-1) will face off today at 3:00 p.m. EST at Anfield in Liverpool, England.

Liverpool is favored at a -334 price, with the over/under set at 2.5 (-300o / +240u) goals.

Let's get into my PSV vs. Liverpool prediction.

PSV vs Liverpool Prediction

Picks: Liverpool To Win & Both Teams To Score
My Liverpool vs. PSV best bet is a parlay backing Liverpool to win the game outright and both teams to score.

PSV vs. Liverpool Odds

PSV Logo
Wednesday, Nov 26
3 p.m. ET
Liverpool Logo
PSV Odds
SpreadTotalMoneyline
2.5
-300o / 240u
+700
Liverpool Odds
SpreadTotalMoneyline
2.5
-300o / 240u
-334
Odds via bet365. Get up-to-the-minute SOCCER odds here.
bet365 Logo

PSV vs. Liverpool Picks, Parlay

Leg 1: Liverpool to Win
Leg 2: Both Teams to Score

Pressure continues to grow on Arne Slot as Liverpool’s slump continues. Winning this game will alleviate some of the pressure on the Anfield boss, and they have the personnel to do just that. However, the defensive issues remain, so we are backing a home win with both teams scoring in our Liverpool vs PSV predictions.

Despite enduring a difficult start to the season, Liverpool remains a force on home turf, winning seven of its 10 competitive games at Anfield. The Reds beat Real Madrid on matchday four of the Champions League, and should have scored a few more, but for the heroics of Thibaut Courtois.

However, Nottingham Forest were able to take advantage of Liverpool’s weaknesses at the weekend. Sean Dyche’s side had just 25% possession, but managed to score three goals. PSV can go direct and exploit the Reds’ defensive frailty here.

PSV has found the net in all four of its Champions League matches so far. The team’s matches have averaged 4.0 goals per game, well above the competition average of 3.42. The Liverpool clash looks set to be another goal-friendly affair.

Peter Bosz’s side is a big underdog in this game, but backing the visitors to score gives a more appealing price for a Liverpool win. PSV has scored in 16 of its 17 competitive matches this season, averaging 2.94 goals per game.

There is no room for Liverpool complacency as the calls to sack Slot get louder. Expect the Reds to bounce back after the woeful showing against Forest, but a clean sheet appears unlikely.

Playbook

PSV vs. Liverpool Projections

Projected Chance of Winning

PSVDrawLiverpool
9.3%13.1%77.6%

Projected Total Goals

PSVTotal GoalsLiverpool
0.913.852.94

PSV vs. Liverpool Betting Analysis

After two 3-0 defeats in the Premier League against Manchester City and Nottingham Forest, Liverpool is seeking redemption in the Champions League against PSV.

The Reds are virtually out of the title race in England, but have a strong chance of qualifying for the Round of 16 without needing to go through the playoffs.

With nine points, Liverpool is eighth in the standings, having already beaten both Madrid teams at home this year.

18th-placed PSV has five points, but it has bounced back well after an initial home defeat to Union SG. Peter Bosz's team is unbeaten in 11 games and leads the Eredivisie by six points over Feyenoord.

In the 2024/25 season, PSV defeated Liverpool 3-2 in the final game of the league phase when the Premier League outfit was already among the top eight. According to bookmakers, the match is expected to be one-sided in favour of the hosts. Indeed, the latest Liverpool vs PSV odds give Arne Slot’s side about a 77% chance of winning the game.

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