2021 Australian Open Betting Guide: Odds on Novak Djokovic, Naomi Osaka & More to Win Down Under

The 2021 Australian Open is a very different one to say the least, with COVID-19 protocols creating perhaps the most unique set of circumstances in Australian Open history.

Despite the very different vibe surrounding the tournament, we see familiar faces still alive and atop the oddsboards in both the men's and women's tournament..

Men's No. 1 Novak Djokovic looks to continue his dominance with his third-straight Australian Open title, while Naomi Osaka faces a marquee matchup in the semifinals in her quest for a second title down under.

Djokovic had an action-packed, expressive win over Alexander Zverev in the quarterfinals, which included one of the more memorable racket smashes in the history of the tournament.

Though he is still making headlines off the court, Djokovic is the runaway favorite in the men's bracket at -121 on DraftKings.

The women's side of the tournament looks much more open, with 2019 Australian Open winner Osaka coming in as the favorite with +145 odds. Osaka had a dominant win over Su-Wei Hsieh in the quarterfinals, setting up her clash with Serena Williams.

Here's a look at the odds as of Tuesday, Feb. 16 at 4:15 p.m. ET and via DraftKings:

Australian Open Odds

Men's Bracket

Women's Bracket