US Open Odds, Best Bets | Tennis Picks & Predictions

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It's been a whirlwind start to the US Open, with incredible matches coming thick and fast across the ground at the Billie Jean King USTA National Tennis Center in New York.

Thursday's US Open slate is set to bring more excitement and thrilling contests, and our tennis betting experts have found a number of bets with value ahead of the second round matches.

Here are our US Open best bets ahead of Thursday's US Open matches.

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US Open Odds, Best Bets

Matches are listed in chronological order. Match times are subject to change, and many will be played after the projected start time. Read here for advice on watching the US Open. Please bet responsibly.

John Isner vs Michael Mmoh

11 a.m. ET

In the final US Open of his career, John Isner will battle with Michael Mmoh for a spot in the third round.

Kenny Ducey breaks down the all-American clash.

Jannik Sinner vs Lorenzo Sonego

11 a.m. ET

Under the radar US Open contender Jannik Sinner will meet his countryman in Lorenzo Sonego on Louis Armstrong Stadium.

Read on for a full match preview and pick.

Jack Draper vs Hubert Hurkacz

11 a.m. ET

Will healing British tennis star Jack Draper be able to pull an upset over five-set first round victor Hubert Hurkacz?

Ducey breaks down his thoughts.

Clara Tauson vs Peyton Stearns

11 a.m. ET

This is a massive opportunity for both Clara Tauson and Peyton Stearns as the two youngters look to pick up crucial Grand Slam wins.

David Gertler discusses why he's backing the Dane.

Grigor Dimitrov vs Andy Murray

12 p.m. ET

It may feel like 2014 at this US Open, but we're still in 2023 and we have a veteran clash on Ashe.

Grigor Dimitrov meets Andy Murray for a spot in the third round.

Marketa Vondrousova vs Martina Trevisan

1 p.m. ET

Wimbledon champion Marketa Vondrousova will meet clay-court specialist Martina Trevisan with a clear path through to the third round.

Should we expect dominance from the lefty?

Tennis Picks & Predictions

Alex de Minaur vs Yibing Wu

1:30 p.m. ET

Chinese tennis prodigy Yibing Wu got past Dusan Lajovic in five sets to open his US Open campaign, but Alex de Minaur is an even stiffer test.

See why our expert believes he'll push the feisty Aussie.

Madison Keys vs Yanina Wickmayer

2 p.m. ET

Yanina Wickmayer retired from the final round of US Open qualifying with a back ailment, but now she's in the second round thanks to a lucky loser slot, some fast recovery and a first round win.

Does she have any hope against former finalist Madison Keys?

Nicolas Jarry vs Alex Michelsen

2 p.m. ET

One of the youngest Americans in the draw, Alex Michelsen has already picked up a debut Grand Slam win.

Jon Reid details his best bet for Michelsen's match with Nicolas Jarry.

Marie Bouzkova vs Petra Martic

3 p.m. ET

The ever-solid Marie Bouzkova takes on the crafty Petra Martic in an intriguing mix of styles.

Who has the edge in this contest?

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