Brewers vs. Cardinals Odds & Betting Predictions - September 20, 2025

Brewers at Cardinals

11:15 pm • FDSMW

Milwaukee Brewers

94-60

3 - 2

St. Louis Cardinals

75-79

pitcher		team	era	w-l
M.Mikolas			4.80	8-10
C.Patrick			3.64	3-8

MatchupOpenSpreadTotalMoneyline
Brewers 94-60	-1.5	-1.5+114	o8.5-120	-145
Cardinals 75-79	u8.5	+1.5-134	u8.5+100	+121

Saturday 11:15 p.m.

September 20, 2025

Busch StadiumSt. Louis

MIL -140

0.5u

Mikolas with a 4.80 ERA but 5.27 xERA. He did beat Brewers last start but underlying numbers just scream negative regression candidate. On the flip side, Chad Patrick has a 4.03 xERA. Paying a bit of juice here to back the Brewers but a spot I’m willing to do it.

STL +130

Saturday's MLB Best Bets
Action Network Staff•
Sep 20, 2025 UTC

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MLB Public Betting

Cardinals are 3-2 in their last 5 games.
Cardinals are 3-2 in their last 5 games against the spread
Cardinals are 37-38 in their road games against the spread
The totals have gone OVER in 2 of Cardinals' last 5 games
The totals have gone OVER in 39 of Cardinals' 79 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Cardinals	76-78	39-40	37-38	25-41	50-37
Brewers	86-68	39-39	47-29	42-48	43-20

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Cardinals	77-70-7	39-37-3	38-33-4	33-28-5	43-42-2
Brewers	75-74-5	37-38-3	38-36-2	49-39-2	26-34-3

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Cardinals	75-79	43-36	32-43	33-33	41-46
Brewers	94-60	51-27	43-33	57-33	36-27

date	opponent	score	spread	over/under	moneyline
Sep 20th	MIL	W 7-1	+1.5 W	O 7.5	-
Sep 17th	CIN	L 2-6	+1.5 L	U 8.5	CIN +102
Sep 16th	CIN	W 3-0	+1.5 W	U 8	STL +105
Sep 15th	CIN	L 6-11	+1.5 L	O 8.5	CIN -113
Sep 14th	@MIL	W 3-2	+1.5 W	U 8.5	STL +160

Jordan Montgomery
SP
Montgomery is out for season with elbow
Out for Season
Easton McGee
SP
McGee is out with arm
Out
Garrett Mitchell
CF
Mitchell is out with oblique
Out

Masyn Winn
SS
Masyn Winn (knee) has been scratched Friday.
Out

See more MLB Injuries

PITCHER	PC	IP	K	ER
RC.Patrick, P	56	4.1	3	2
LA.Ashby, P	39	2.2	1	0
RA.Uribe, P	17	1	2	0
LJ.Koenig, P	16	2	1	0

HITTERS	H-AB	R	RBI
1S.Frelick, RF	1-5	0	0
2J.Chourio, CF	1-5	1	0
2J.Chourio, LF	1-5	1	0
3C.Yelich, DH	0-5	0	0
4W.Contreras, C	1-3	0	0
4D.Jansen, C	0-1	0	0
5B.Turang, 2B	1-5	0	1
6C.Durbin, 3B	1-5	1	0
7J.Bauers, LF	1-4	1	0
7B.Perkins, CF	0-0	0	0
8A.Vaughn, 1B	1-1	0	1
8A.Monasterio, PR	0-0	0	0
8A.Monasterio, 1B	0-0	0	0
9J.Ortiz, SS	2-4	0	1

PITCHER	PC	IP	K	ER
RM.Mikolas, P	95	5	3	2
RK.Leahy, P	24	2	1	0
RR.O'Brien, P	19	1.1	1	0
LJ.Romero, P	17	1.2	0	0

HITTERS	H-AB	R	RBI
1B.Donovan, 2B	1-5	0	1
2I.Herrera, DH	1-4	1	0
3A.Burleson, LF	1-4	0	0
3A.Burleson, 1B	1-4	0	0
4N.Arenado, 3B	2-4	0	1
5T.Saggese, SS	1-4	0	0
6N.Gorman, 1B	0-4	0	0
6N.Church, LF	0-0	0	0
6N.Church, CF	0-0	0	0
7P.Pages, C	1-4	1	0
8J.Walker, RF	2-3	0	0
9V.Scott, CF	0-1	0	0
9Y.Pozo, PH	0-1	0	0
9L.Nootbaar, LF	0-0	0	0