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Cardinals vs. Reds Odds & Betting Predictions - May 23, 2026

Cardinals at Reds

11:15 pm • FOX

St. Louis Cardinals

0-0
6
6 - 7

Cincinnati Reds

0-0
7
Starting Pitchers
pitcherteameraw-l
Chase Petty logoC.PettyCincinnati Reds logo4.831-2
Kyle Leahy logoK.LeahySt. Louis Cardinals logo3.6610-5

Cardinals at Reds Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Cardinals
0-0
+1.5
-1.5+140
o9.5-120
-110
Reds
0-0
u9.5
+1.5-170
u9.5-102
-114
location pinSaturday 11:15 p.m.
May 23, 2026
Great American Ball ParkCincinnati
Cardinals vs. Reds Expert Picks
Sean Zerillo
Sean Zerillo
Last 30d: 134-117-6 (+6.6u)
Over 9.5-102
0.26u
G2. Small to -115 before seeing G1 lineups…may increase
Ryan Minion
Ryan Minion
Last 30d: 255-269-8 (-1.9u)
S.Stewart o2.5 Hits + Runs + RBIs+112
$1.00
S.Stewart o0.5 HR+340
$1.00
Frank Ammirante
Frank Ammirante
Last 30d: 103-94-0 (-4.9u)
CIN u2.5 (F5)-125
1.25u
Player Prop Savant
Player Prop Savant
Last 30d: 82-76-0 (-0.1u)
Over 7 (Live)-136
1u
Over 5.5 (Live)-118
1u
CIN o4.5-117
1u
Alex Hinton
Alex Hinton
Last 30d: 105-111-0 (+7.5u)
STL -110
0.5u

Cardinals vs. Reds Previews & Analysis

  • The Leadoff: Trollo's MLB Breakdown and Bets for Saturday article feature image

    The Leadoff: Trollo's MLB Breakdown and Bets for Saturday

    Matt Trollo•
    May 23, 2026 UTC
  • Our 4 MLB Best Bets for Saturday Afternoon article feature image

    Our 4 MLB Best Bets for Saturday Afternoon

    Action Network Staff•
    May 23, 2026 UTC
  • Cardinals vs Reds Game 2 Preview and Pick article feature image

    Cardinals vs Reds Game 2 Preview and Pick

    Alex Hinton•
    May 23, 2026 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Cardinals vs. Reds Public Betting Percentages

Away Logo

Cardinals

Public

Home Logo

Reds

57%

Bets%

43%

Money%

MLB Public Betting Right Arrow

Betting Trends

  • Reds are 2-3 in their last 5 games.
  • Reds are 4-1 in their last 5 games against the spread
  • Reds are 44-37 in their road games against the spread
  • The totals have gone OVER in 2 of Reds' last 5 games
  • The totals have gone OVER in 40 of Reds' 81 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Reds		82-8038-4344-3718-2364-56
Cardinals		86-7641-4045-3617-3468-40

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Reds		84-75-340-39-244-36-126-14-158-60-2
Cardinals		74-82-636-42-338-40-324-26-148-55-5

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Reds		75-8738-4337-4423-1852-68
Cardinals		77-8538-4339-4225-2651-57

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 23rdSTLL 1-8+1.5 LU 10STL -114
May 20th@PHIW 9-4+1.5 WO 9.5CIN +129
May 19th@PHIW 4-1+1.5 WU 8.5CIN +122
May 18th@PHIL 4-5-1.5 LU 10PHI +104
May 17th@CLEL 3-10+1.5 LO 8.5CLE +135

Reds vs. Cardinals Injury Updates

Reds Injuries

  • Carson Spiers
    RP

    Spiers is out with shoulder

    Out

Cardinals Injuries

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    Cardinals vs. Reds Box Score
    Cardinals Player Stats
    Projected
    PITCHERPCIPKER
    Kyle Leahy logoRK.Leahy, P87585
    Justin Bruihl logoLJ.Bruihl, P130.101
    Gordon Graceffo logoRG.Graceffo, P170.210
    Ryan Fernandez logoRR.Fernandez, P24240
    JoJo Romero logoLJ.Romero, P12110
    Riley O'Brien logoRR.O'Brien, P201.120
    HITTERSH-ABRHRRBI
    JJ Wetherholt logo1J.Wetherholt, 2B1-5000
    Ivan Herrera logo2I.Herrera, DH1-5100
    Alec Burleson logo3A.Burleson, 1B1-4100
    Jordan Walker logo4J.Walker, RF3-4214
    Nolan Gorman logo5N.Gorman, 3B1-5000
    Thomas Saggese logo5T.Saggese, PR0-0000
    Thomas Saggese logo5T.Saggese, 3B0-0000
    Masyn Winn logo6M.Winn, SS0-4001
    Bryan Torres logo7B.Torres, LF1-4000
    Pedro Pages logo8P.Pages, C0-3000
    Jose Fermin logo8J.Fermin, PH1-1111
    Yohel Pozo logo8Y.Pozo, C0-1000
    Victor Scott logo9V.Scott, CF0-4100
    Reds Player Stats
    Projected
    PITCHERPCIPKER
    Chase Petty logoRC.Petty, P62514
    Brock Burke logoLB.Burke, P261.100
    Graham Ashcraft logoRG.Ashcraft, P291.230
    Tony Santillan logoRT.Santillan, P28112
    Pierce Johnson logoRP.Johnson, P23210
    HITTERSH-ABRHRRBI
    Blake Dunn logo1B.Dunn, CF2-6101
    Blake Dunn logo1B.Dunn, RF2-6101
    Elly De La Cruz logo2E.De La Cruz, SS2-4113
    JJ Bleday logo3J.Bleday, DH0-5000
    Sal Stewart logo4S.Stewart, 3B0-2100
    Sal Stewart logo4S.Stewart, 1B0-2100
    Nathaniel Lowe logo5N.Lowe, 1B2-4112
    Eugenio Suarez logo5E.Suarez, PH0-1000
    Eugenio Suarez logo5E.Suarez, 3B0-1000
    Matt McLain logo6M.McLain, 2B0-5000
    Will Benson logo7W.Benson, RF1-2000
    Spencer Steer logo7S.Steer, PH1-3200
    Spencer Steer logo7S.Steer, LF1-3200
    P.J. Higgins logo8P.Higgins, C1-3100
    TJ Friedl logo9T.Friedl, LF0-1000
    Dane Myers logo9D.Myers, PH1-2001
    Dane Myers logo9D.Myers, CF1-2001

    Cardinals vs. Reds Odds Comparison

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    Cardinals at Reds Team Totals

    MatchupOverUnder
    Cardinals
    0-0
    N/A
    N/A
    Reds
    0-0
    N/A
    N/A