Guardians vs. White Sox Odds & Betting Predictions - October 7, 2026

Guardians at White Sox

8:00 pm • TBS
@
Starting Pitchers
pitcherteameraw-l
Sean Newcomb logoS.NewcombChicago White Sox logo6.000-0
Daniel Espino logoD.EspinoCleveland Guardians logo0.000-0

Guardians at White Sox Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Guardians
0-2
-1.5
+1.5-205
o8-105
+109
White Sox
2-0
u8
-1.5+167
u8-112
-130
location pinWednesday 8:00 p.m.
October 07, 2026
Rate FieldChicago
thermometer image73°Fahrenheit
rain image0%Rain
wind image6Wind
Guardians vs. White Sox Expert Picks
Sandy Plashkes
Sandy Plashkes
Last 30d: 96-74-3 (+49.7u)
CLE o3.5-120
1.2u
Bet Labs
Bet Labs
Last 30d: 9-11-1 (-3.3u)
CLE +110
0.91u
Brandon Kravitz
Brandon Kravitz
Last 30d: 51-56-1 (-0.0u)
CLE +113 (F5)
0.5u
Grant Neiffer
Grant Neiffer
Last 30d: 34-109-4 (+7.6u)
M.Murakami o0.5 HR+410
0.25u
Sandy Plashkes
Sandy Plashkes
Last 30d: 96-74-3 (+49.7u)
CLE +114
1u
Kyle Murray
Kyle Murray
Last 30d: 149-130-8 (+19.1u)
Under 8-115
1.15u
Payoff Pitch Podcast
Payoff Pitch Podcast
Last 30d: 60-134-2 (-15.7u)
A.Benintendi u0.5 Hits-125
1u
Nick Martin
Nick Martin
Last 30d: 16-15-0 (+3.3u)
CLE -0.5 (F5)+134
1u
Doug Ziefel
Doug Ziefel
Last 30d: 329-391-9 (+3.5u)
A.Benintendi o0.5 Total Bases+135
0.37u
T.Bazzana o0.5 SB+900
0.1u
B.Montgomery o0.5 SB+1600
0.1u
Collin Whitchurch
Collin Whitchurch
Last 30d: 82-109-1 (+0.0u)
A.Benintendi u0.5 Hits-125
0.63u
Doug Ziefel
Doug Ziefel
Last 30d: 329-391-9 (+3.5u)
M.Murakami u1.5 Hitter Strikeouts-110
0.55u
B.Montgomery o0.5 Hitter Strikeouts-115
0.57u
Over 7.5-118
0.59u
Adam Kaufman
Adam Kaufman
Last 30d: 189-201-5 (-22.2u)
CWS -115
0.57u
Sean Zerillo
Sean Zerillo
Last 30d: 92-109-4 (-6.1u)
Under 8-112
0.56u
Bet to 7.5 (-105)
CLE +108
0.5u
Bet to -105

Guardians vs. White Sox Previews & Analysis

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    Grant Neiffer's 4 Home Run Picks for Wednesday

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  • Guardians vs White Sox: Nick's Pick for AL Division Series Game 3 article feature image

    Guardians vs White Sox: Nick's Pick for AL Division Series Game 3

    Nick Martin•
    Oct 7, 2026 UTC
  • Our 4 MLB Best Bets for Wednesday's Division Series Games article feature image

    Our 4 MLB Best Bets for Wednesday's Division Series Games

    Action Network Staff•
    Oct 7, 2026 UTC
  • +540 Early Home Run Pick Fuels 3 PRO Plays article feature image

    +540 Early Home Run Pick Fuels 3 PRO Plays

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Prop Odds Comparison

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Line Movement Tracker

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Guardians vs. White Sox Public Betting Percentages

Away Logo

Guardians

Public

23%

Bets%

77%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
White Sox
92-7049-3243-3828-2363-46
Guardians
79-8336-4543-3843-5536-24

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
White Sox
92-69-145-35-147-3427-23-163-46
Guardians
77-8542-3935-4648-5027-33

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
White Sox
4-048-3336-4530-2153-56
Guardians
0-241-4044-3755-4330-30

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Oct 5th@CLEW 4-3+1.5 WO 6.5CWS +130
Oct 3rd@CLEW 3-0+1.5 WU 6.5CWS +125
Sep 30th@HOUW 7-3+1.5 WO 7.5CWS +130
Sep 29th@HOUW 6-3-1.5 WO 8.5CWS +102
Sep 27thCOLW 4-2-1.5 WU 8.5CWS -164

Guardians vs. White Sox Injury Updates

Guardians Injuries

    White Sox Injuries

    • Mike Vasil
      RP

      Vasil is out with elbow

      Out

    • Ky Bush
      SP

      Bush is out with elbow

      Out

    • Brooks Baldwin
      LF

      Baldwin is out with elbow

      Out

    • Drew Thorpe
      SP

      Thorpe is out with elbow

      Out

    Guardians vs. White Sox Starting Lineups
    Guardians Starting Lineup
    Projected
    PITCHERW-LERAWHIPK/9
    Daniel Espino logoRD.Espino, P0-04.111.23914.67
    HITTERSAVGOBPSLGHR
    Steven Kwan logo1S.Kwan, CF.282.382.3493
    Jose Ramirez logo2J.Ramirez, 3B.235.320.36812
    Chase DeLauter logo3C.DeLauter, RF.287.363.45716
    Jo Adell logo4J.Adell, DH.244.324.4177
    Nathaniel Lowe logo5N.Lowe, 1B.226.275.3765
    Angel Martinez logo6A.Martinez, LF.254.290.46518
    Travis Bazzana logo7T.Bazzana, 2B.245.335.40815
    Patrick Bailey logo8P.Bailey, C.228.292.3909
    Brayan Rocchio logo9B.Rocchio, SS.253.313.39115
    White Sox Starting Lineup
    Projected
    PITCHERW-LERAWHIPK/9
    Sean Newcomb logoLS.Newcomb, P2-53.091.1858.37
    HITTERSAVGOBPSLGHR
    Sam Antonacci logo1S.Antonacci, DH.277.370.3968
    Miguel Vargas logo2M.Vargas, 3B.250.363.47433
    Munetaka Murakami logo3M.Murakami, 1B.207.347.47835
    Kyle Teel logo4K.Teel, C.210.336.3615
    Chase Meidroth logo5C.Meidroth, 2B.276.350.41516
    Tristan Peters logo6T.Peters, CF.265.337.43712
    Braden Montgomery logo7B.Montgomery, RF.226.312.3506
    Randal Grichuk logo8R.Grichuk, LF.194.212.3230
    Colson Montgomery logo9C.Montgomery, SS.197.282.40331

    Guardians vs. White Sox Odds Comparison

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    Guardians at White Sox Team Totals

    MatchupOverUnder
    Guardians
    0-2
    N/A
    N/A
    White Sox
    2-0
    N/A
    N/A