Mariners vs. Astros Odds & Betting Predictions - September 20, 2025

Mariners at Astros

12:10 am • SCHN

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Seattle Mariners

@

Houston Astros

pitcher		team	era	w-l
H.Brown			0.00	0-0
B.Woo			0.00	0-0

MatchupOpenSpreadTotalMoneyline
Mariners 82-68	N/A	N/A	N/A
Astros 82-69	N/A	N/A	N/A

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Saturday 12:10 a.m.

September 20, 2025

Daikin ParkHouston

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86°Fahrenheit

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0%Rain

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9Wind

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MLB Public Betting

Astros are 3-2 in their last 5 games.
Astros are 3-2 in their last 5 games against the spread
Astros are 42-33 in their road games against the spread
The totals have gone OVER in 3 of Astros' last 5 games
The totals have gone OVER in 33 of Astros' 76 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Astros	77-74	35-41	42-33	40-57	37-15
Mariners	62-88	34-41	28-47	38-66	23-20

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Astros	68-76-7	33-41-2	35-35-5	44-51-2	22-25-5
Mariners	81-63-6	38-32-5	43-31-1	52-46-6	27-16

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Astros	82-69	44-32	38-37	53-44	29-23
Mariners	82-68	48-27	34-41	59-45	21-22

date	opponent	score	spread	over/under	moneyline
Sep 16th	TEX	W 6-3	-1.5 W	O 8.5	HOU -132
Sep 14th	@ATL	L 3-8	-1.5 L	O 9	ATL -137
Sep 13th	@ATL	W 6-2	-1.5 W	U 8.5	HOU -139
Sep 12th	@ATL	W 11-3	+1.5 W	O 8.5	HOU +115
Sep 11th	@TOR	L 0-6	+1.5 L	U 8.5	TOR +140

Pedro Leon
RF
Leon is out with knee
Out
Hayden Wesneski
RP
Wesneski is out with elbow
Out

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MatchupOverUnder
Mariners 82-68	N/A	N/A
Astros 82-69	N/A	N/A