The Washington Nationals host the Houston Astros on July 6, 2026. First pitch from Nationals Park is scheduled for 6:45 p.m. EDT. The game will be broadcast on NATS.
The Astros are favored by -120 on the moneyline and by -1.5 on the run line. The Astros are -100 on the moneyline and -1.5 on the run line. The total is set at 10 runs.
Find my MLB picks and Astros vs Nationals prediction below, as well as probable pitchers, weather report, and more.
- Astros vs Nationals Pick: Over 10 (-110)
My Astros vs Nationals best bet is on the run total over. Make sure to find the best odds by checking our live MLB odds page.
Astros vs Nationals Odds
| Astros Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +155 | 10 -101o / -118u | -100 |
| Nationals Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +155 | 10 -101o / -118u | -120 |
- Astros vs Nationals moneyline: Astros -100, Nationals -120
- Astros vs Nationals over/under: 10 (-101o / -118u)
- Astros vs Nationals spread: Astros -1.5 (+155), Astros -1.5 (+155)
Astros vs Nationals Probable Pitchers
| RHP Mike Burrows (HOU) | Stat | RHP Miles Mikolas (WSN) |
|---|---|---|
| 4-8 | W-L | 2-7 |
| -0.1 | fWAR (FanGraphs) | -0.5 |
| 5.58/4.58 | ERA / xERA | 5.44/4.79 |
| 5.48/4.81 | FIP / xFIP | 5.38/4.56 |
| 9.8% | K-BB% | 8.4% |
| 37.5% | GB% | 44.0% |
| .311 | BABIP | .269 |
| 94 | Stuff+ | 90 |
| 97 | Location+ | 111 |

Astros vs Nationals Pick, Betting Analysis
It's Yordan Alvarez vs. Miles Mikolas. The best hitter in the game this year against, arguably, the worst right-handed pitcher. But what are you going to do? Bet on Yordan Alvarez at +190 or whatever ridiculous line this will be set at? Are you a fish?
The simpler path is just to take the total. I don't think the books can comfortably price this one right. There have been 11.4 runs scored per game in DC this year. And now we get Mikolas hosting another horribly righty Mike Burrows. This is two of the worst pitching staffs in the league going up against two quite capable offenses.
I expected this total to be 11.5 or something; instead, we get 10. So I'm taking that as soon as I can! Look for the best lines, be smart, but this game is primed for a dozen dudes crossing home plate.
Pick: Over 10 (-110)
If you must bet homers and you're not super price-conscious, you can take the obvious parlay here. James Wood (+247) and Yordan Alvarez (+231) are #1 and #3 in my home run projections tonight (Hunter Goodman is #2).
They're both in elite spots against fly-ball righties and against bad bullpens behind them. The parlay there gives you a 10:1 return on your money on DraftKings. And you can find slightly better prices elsewhere if you're not a DK bettor.
Pick: James Wood and Yordan Alvarez HR Parlay (+900)































