The Chicago White Sox host the Baltimore Orioles on September 15, 2025. First pitch from Rate Field is scheduled for 7:40 p.m. EDT; the game will be broadcast on CHSN.
The Orioles are on a three-game losing streak and will send Kyle Bradish to the mound against the White Sox in the opener of this series.
Find my MLB betting preview and Orioles vs White Sox prediction below, as well as probable pitchers, betting trends, injury reports and more.
My Orioles vs White Sox Prediction
- Orioles vs White Sox pick: Under 8 (-105)
My Orioles vs White Sox best bet is Under 8 total runs in this game. Make sure to find the best odds by checking our live MLB odds page.
Orioles vs White Sox Odds
| Orioles Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +115 | 8 -115o / -105u | -155 |
| White Sox Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -135 | 8 -115o / -105u | +130 |
Orioles vs White Sox Projected Starting Pitchers
| RHP Kyle Bradish (BAL) | Stat | RHP Sean Burke (CHW) |
|---|---|---|
| 0-1 | W-L | 4-10 |
| 0.5 | fWAR (FanGraphs) | 0.6 |
| 2.65 / 2.66 | ERA / xERA | 4.35 / 5.16 |
| 2.91 / 3.10 | FIP / xFIP | 5.05 / 4.89 |
| 0.94 | WHIP | 1.47 |
| 26.2 | K-BB% | 10.5 |
| 35.0 | GB% | 34.8 |
| 93 | Stuff+ | 91 |
| 115 | Location+ | 101 |
Orioles vs White Sox Preview
The Orioles have only produced 23 runs in their past nine games for an average of 2.55 per contest. They are 19th this season in wRC+ but are 25th in September with an 81 wRC+ rating.
Meanwhile, the White Sox rank 27th in wRC+ in 2025 with an 88 rating and will finish the season as one of the worst offenses in baseball.
Kyle Bradish is the confirmed starter today for Baltimore, and he hasn't missed a beat since returning from Tommy John surgery.
Bradish had sub-3.00 ERAs in 2023 and 2024, and is doing it again this season in his three starts so far. He allowed just two earned runs in each of his first two outings and is coming off an excellent game against the Pirates.
The right-hander completed seven innings and gave up just four hits and one run while striking out six batters, so he should do well against this Chicago lineup.
This aligns with our Bet Labs recommendation to go with the under.
This system in MLB targets evening games where public interest in the over is muted, recent home team scoring has run slightly hot, and subtle environmental signals align with lower-scoring outcomes.
Games start between 7:00 and 11:59 PM ET, and the market over percentage sits below 50, suggesting minimal public pressure on inflated totals.
The home team has hit the over in just 20 to 67 of its last five games, and their previous outing landed modestly over the total by only 1.5 to 9 runs —indicators of recent scoring that may overstate offensive strength.
Meanwhile, the wind direction — whether blowing in, across the field, or neutral — paired with moderate temperatures between 26 and 74, introduces natural resistance to run scoring.
The home team is competitively priced on the moneyline and has a wide win rate window, providing no clear power imbalance that might inflate totals.
When layered together, these filters isolate a soft edge in a game environment where bettors overlook the under due to recency bias and lack of extreme public conviction.
Pick: Under 8 (-105, bet365)
Orioles vs White Sox Betting Trends
