The Milwaukee Brewers host the Cincinnati Reds on September 26, 2025. First pitch from American Family Field is scheduled for 8:10 p.m. EDT; the game will be broadcast on FDSWI.
The Reds need to catch the Mets in the NL Wild Card race. However, in order to do it, they will have to go through the best team in the majors: the Brewers.
Find my MLB betting preview and Reds vs Brewers prediction below, as well as probable pitchers, betting trends, injury reports and more.
My Reds vs Brewers Prediction
- Reds vs Brewers pick: Under 8 (-115)
My Reds vs Brewers best bet is Under 8 total runs in this game. Make sure to find the best odds by checking our live MLB odds page.
Reds vs Brewers Odds
| Reds Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -155 | 8 -105o / -115u | +145 |
| Brewers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +130 | 8 -105o / -115u | -165 |
Reds vs Brewers Projected Starting Pitchers
| RHP Zack Littell (CIN) | Stat | RHP Quinn Priester (MIL) |
|---|---|---|
| 10-8 | W-L | 13-2 |
| 1.3 | fWAR (FanGraphs) | 1.7 |
| 3.86 / 4.47 | ERA / xERA | 3.25 / 3.63 |
| 4.93 / 4.34 | FIP / xFIP | 4.08 / 3.80 |
| 1.10 | WHIP | 1.21 |
| 13.1 | K-BB% | 12.5 |
| 40.3 | GB% | 56.6 |
| 85 | Stuff+ | 98 |
| 104 | Location+ | 100 |
Reds vs Brewers Preview
After a disappointing series loss to the Pirates, Cincinnati must win this series against the Brewers.
They will send Zack Littell to the mound tonight and are confident he can keep his dominance over the Milwaukee lineup.
Littell already faced the Brewers twice this season, allowing just three runs and 10 hits across 12 innings combined.
On the other side, Quinn Priester will start for Milwaukee, and he's also had success against Cincinnati this season. In his two starts combined, Priester gave up three runs and eight hits in 10 and 1/3 innings.
On top of that, the Reds are 24th in wRC+ in 2025 and have not improved much lately, sitting at the 23rd spot in the September rankings.
This aligns with our Bet Labs recommendation to go with the under tonight.
This system in MLB targets evening games where public interest in the over is muted, recent home team scoring has run slightly hot, and subtle environmental signals align with lower-scoring outcomes.
- Games start between 7:00 and 11:59 PM ET, and the market over percentage sits below 50, suggesting minimal public pressure on inflated totals.
- The home team has hit the over in just 20 to 67 of its last five games, and their previous outing landed modestly over the total by only 1.5 to 9 runs —indicators of recent scoring that may overstate offensive strength.
- Wind direction — whether blowing in, across the field, or neutral — paired with moderate temperatures between 26 and 74, introduces natural resistance to run scoring.
- The home team is competitively priced on the moneyline and has a wide win rate window, providing no clear power imbalance that might inflate totals.
When layered together, these filters isolate a soft edge in a game environment where bettors overlook the under due to recency bias and lack of extreme public conviction.
Pick: Under 8 (-115, bet365)
Reds vs Brewers Betting Trends
