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Guardians vs Tigers Prediction, Pick, MLB Odds for Wednesday, August 12

Guardians vs Tigers Prediction, Pick, MLB Odds for Wednesday, August 12 article feature image
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Jul 24, 2026; Detroit, Michigan, USA; Detroit Tigers pitcher Framber Valdez (59) in the dugout in the first inning against the Kansas City Royals at Comerica Park. Mandatory Credit: Rick Osentoski-Imagn Images

The Detroit Tigers host the Cleveland Guardians on August 12, 2026. First pitch from Comerica Park is scheduled for 6:40 p.m. EDT. The game will be broadcast on CLEG.

The Tigers are favored by -120 on the moneyline and by -1.5 on the run line. The Guardians are +110 on the moneyline and +1.5 on the run line. The total is set at 8 runs.

Find my MLB picks and Guardians vs Tigers prediction below, as well as probable pitchers, weather report, and more.


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Guardians vs Tigers Prediction

  • Guardians vs Tigers Pick: NRFI (-138)

My Guardians vs Tigers best bet is on no runs in the first inning. Make sure to find the best odds by checking our live MLB odds page.


Guardians vs Tigers Odds

Guardians Logo
Wednesday, Aug 12
6:40 p.m. ET
CLEG
Tigers Logo
Guardians Odds
SpreadTotalMoneyline
+1.5
-210
8
-120o / -102u
+110
Tigers Odds
SpreadTotalMoneyline
-1.5
+172
8
-120o / -102u
-120
Odds via FanDuel. Get up-to-the-minute MLB odds here.
FanDuel Logo
  • Guardians vs Tigers moneyline: Guardians +110, Tigers -120
  • Guardians vs Tigers over/under: 8 (-120o / -102u)
  • Guardians vs Tigers spread: Tigers -1.5 (+172), Guardians +1.5 (-210)

Guardians vs Tigers Probable Pitchers

Foster Griffin (LHP, CLE)StatFramber Valdez (LHP, DET)
12-4W-L7-7
1.7fWAR (FanGraphs)1.5
3.31 / 4.08ERA / xERA4.17 / 4.31
4.21 / 3.74FIP / xFIP4.04 / 4.15
16.3%K-BB%10.4%
44.7%GB%53.6%
.262BABIP.303
98Stuff+103
102Location+97

Guardians vs Tigers MLB Betting Preview, Prediction

Left-hander Foster Griffin will take the mound for the Guardians after having just been traded from the Nationals at the trade deadline.

In 23 starts, Griffin has recorded an impressive 3.31 ERA along with a very efficient 1.11 WHIP — both of which rank inside the top-15.

He has fanned 122 batters across his 133.1 innings pitched this season, and is also posting a 12-4 record, which ranks sixth in the Major Leagues among starters.

Framber Valdez will take the mound for the Tigers on Wednesday, surely looking to improve on what has been an up-and-down 2026 campaign thus far.

Prior to this season, Valdez was on a tear throughout his several years pitching for the Astros, having finished with a sub-3.66 ERA in seven of his eight seasons in Houston.

While Valdez has taken a big step back in his first season in Detroit, he is starting to rediscover his elite form, recording a quality start in consecutive outings.

Pick: NRFI (-138)


Guardians vs Tigers Weather


Get the latest coverage on MLB Weather.


Author Profile
About the Author

Ryan graduated from Providence College in 2016 with Bachelor Degrees in Business Economics & Mathematics. It was at Providence where Ryan really first found his passion for sports betting. For a lifelong sports fan with a knack for statistical analysis, he was instantly drawn to the fundamentals of the industry, specifically how sports betting markets functioned and fluctuated. In what primarily started as a recreational hobby, Ryan began studying the ins-and-outs of sports betting markets on a daily basis. He took to Twitter (now X), where he amassed a following for writing a sports betting blog that provided statistical analysis behind his wagers. In spite of seeking employment opportunities elsewhere post graduation, Ryan continued to follow his passion for the statistical analysis of sports betting wagers, eventually deciding to pursue a career in the sports betting industry.

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