Mariners vs Twins Pick, MLB Odds, Betting Analysis for Wednesday, June 25th

Mariners vs Twins Pick, MLB Odds, Betting Analysis for Wednesday, June 25th article feature image
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Photo Credit: Matt Marton-Imagn Images. Pictured: George Kirby

The Minnesota Twins host the Seattle Mariners on June 25, 2025. First pitch from Target Field is scheduled for 7:40 p.m. EDT; the game will be broadcast on ROOT Sports NW.

Find my MLB betting preview and Mariners vs Twins prediction below, as well as probable pitchers, betting trends, injury reports and more.

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My Mariners vs Twins Prediction

  • Mariners vs Twins picks: Under 7.5

My Mariners vs Twins best bet is Under 7.5 runs. Make sure to find the best odds by checking our live MLB odds page.


Mariners vs Twins Odds

Mariners Logo
June 25, 2025
7:40 p.m. EDT
ROOT Sports NW
Twins Logo
Mariners Odds
SpreadTotalMoneyline
+1.5
+164
7.5
-111o / -109u
+107
Twins Odds
SpreadTotalMoneyline
-1.5
-199
7.5
-111o / -109u
-127
Odds via FanDuel. Get up-to-the-minute MLB odds here.
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Mariners vs Twins Projected Starting Pitchers

George KirbyStatJoe Ryan
1-3W-L7-3
0.0fWAR (FanGraphs)1.8
6.16 / 4.64ERA /xERA3.06 / 3.36
4.87 / 3.54FIP / xFIP3.37 / 3.68
1.40WHIP0.91
18.9%K-BB%22.7%
38.2%GB%37.0%
97Stuff+105
112Location+103

The Betting Insider’s Mariners vs Twins Preview

The Twins will hand the ball to Joe Ryan, who’s quietly established himself as one of the more dependable arms in the league this season. Ryan has a 3.06 ERA, a 0.98 WHIP and an elite 28.2% strikeout rate. He leans heavily on his 4-seam fastball, which has held batters to a .179 batting average, and has done an excellent job limiting traffic, walking just 20 batters across 85 1/3 innings this season. 

Opposing him is George Kirby, whose 6.16 ERA doesn’t tell the full story. He’s struggled to return to form since his shoulder injury, but we have seen flashes of the Kirby of old. He allowed just two hits and two earned runs across seven innings vs. the Angels two starts ago, while striking out 14. He remains one of the best command artists in baseball, throwing a first pitch strike 68% of the time and finding the zone with 53% of his pitches, but he's been getting hit harder than usual. His underlying metrics paint a much more encouraging picture as his xFIP sits at 3.54, nearly a point and a half below his FIP of 4.87.


Mariners vs Twins Prediction, Betting Analysis

Both starters will be aided by some very pitcher-friendly conditions, with wind blowing inward at around 10 mph and temperatures sitting below 70 degrees. These weather conditions, as well as the public betting splits, have triggered one of The Betting Insider’s most consistent MLB systems

System) Fair weather unders, wind blowing in, no heavy home favorites or underdogs (62% win rate, 19% ROI)

  • Wind direction is “in”, “from left”, or “from right”
  • Average temperature is no higher than 70 degrees
  • The over/under% is between 1% and 55%
  • The O/U change from open to close is between 0 and -1.5
  • Home ML range is between -210 and +145
  • Since 2020

Pick: Under 7.5 (-105 FD)


Moneyline

I'm going to pass on the Mariners vs Twins moneyline.


Run Line (Spread)

I have no bet on the Mariners vs Twins run line.


Over/Under

As mentioned, we will be backing Under 7.5 in the Mariners vs Twins game.


Mariners vs Twins Betting Trends


Mariners vs Twins starts at 7:40 p.m. EDT on Wednesday, live from Target Field. The game will be broadcast on ROOT Sports NW.


Mariners vs Twins Weather


Get the latest coverage on MLB Weather.


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