The Chicago White Sox host the Minnesota Twins on August 22, 2025. First pitch from Rate Field is scheduled for 7:40 p.m. EDT; the game will be broadcast on MNNT.
The Twins will try to snap their current three-game losing streak tonight against the White Sox in the opener of this weekend's series.
Find my MLB betting preview and Twins vs White Sox prediction below, as well as probable pitchers, betting trends, injury reports and more.
My Twins vs White Sox Prediction
- Twins vs White Sox pick: Under 8.5 (-115)
My Twins vs White Sox best bet is Under 8.5 total runs in this game. Make sure to find the best odds by checking our live MLB odds page.
Twins vs White Sox Odds
| Twins Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +121 | 8.5 -105o / -116u | -139 |
| White Sox Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -147 | 8.5 -105o / -116u | +114 |
Twins vs White Sox Projected Starting Pitchers
| RHP Zebby Matthews (MIN) | Stat | RHP Aaron Civale (CHW) |
|---|---|---|
| 3-4 | W-L | 3-8 |
| 1.0 | fWAR (FanGraphs) | 1.0 |
| 5.06 / 4.08 | ERA / xERA | 4.88 / 4.23 |
| 3.59 / 3.17 | FIP / xFIP | 4.45 / 4.85 |
| 1.44 | WHIP | 1.35 |
| 22.7 | K-BB% | 10.9 |
| 34.1 | GB% | 32.8 |
| 107 | Stuff+ | 97 |
| 102 | Location+ | 98 |
Twins vs White Sox Preview
The Twins are on a troubling two-week slump right now. They rank 21st this season in wRC+ with a 96 rating, but in the last 14 days, they are 29th with 72 wRC+.
They are on a three-game losing streak and scored a combined eight runs in those three contests.
If this keeps going, the White Sox will not need much from starter Aaron Civale to contain them.
Civale had a quality start in his last outing and has allowed three runs or fewer in three of his past four starts.
Zebby Matthews will oppose him for the Twins, and he has given up three runs or fewer in three straight outings. He will go against a Chicago lineup that ranks 28th in MLB in wRC+.
This aligns with our Bet Labs recommendation for the under in this game.
This system capitalizes on an overlooked weather edge in MLB totals betting. It focuses on regular-season games where elevated humidity —ranging from 45 to 95— intersects with moderate temperatures and neutral wind patterns.
Despite assumptions that humidity boosts offense, public bettors are fading these conditions, which actually correlate with suppressed scoring in certain environments.
In these spots, the home team has stayed under in recent games, with their five-game over rate sitting below 40, suggesting low offensive rhythm.
The market has subtly corrected as well, with the total dropping from open to close, and the overall percentage of bets on the over remains modest, between 6 and 29.
These indicators combine to identify under-the-radar under spots where public narratives misalign with actual scoring trends.
Pick: Under 8.5 (-115, Fanatics)
