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MLB Best Bets Today: Predictions & Picks for Rays vs Orioles, Yankees vs Royals, More for Memorial Day

MLB Best Bets Today: Predictions & Picks for Rays vs Orioles, Yankees vs Royals, More for Memorial Day article feature image
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We have a 14-game slate today on this Memorial Day, starting early with Rays vs Orioles at 1:35 PM ET at Camden Yards on MLB.TV and including Rays vs Yankees at 3:40 PM ET on ESPN.

Our experts have analyzed the matchups and found great options for Monday, May 25.

Below are 4 expert MLB best bets today.


MLB Best Bets Today

The team logos in the table below represent each of the matchups that our MLB betting staff is targeting from today's slate of games. Click on the team logos for any of the matchups below to navigate to a specific bet discussed in this article.

GameTime (ET)Pick
Tampa Bay Rays LogoBaltimore Orioles Logo
1:35 PM
St. Louis Cardinals LogoMilwaukee Brewers Logo
2:10 PM
New York Yankees LogoKansas City Royals Logo
3:40 PM
Arizona Diamondbacks LogoSan Francisco Giants Logo
5:05 PM
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game.


Sean Paul's Rays vs Orioles Prediction

Tampa Bay Rays Logo
Monday, May 25
1:35 PM ET
MLB.TV
Baltimore Orioles Logo
Rays ML (-140 or Better)
FanDuel Logo

By Sean Paul

I'm rolling with the Rays as slight road favorites.

Shane McClanahan should contain a struggling Orioles lineup.

If the Rays can remain patient against Kyle Bradish, he'll eventually lose the zone, and Tampa will make him pay.

Pick: Rays ML (-140 or Better)



Derek Carty's Cardinals vs Brewers Pick

St. Louis Cardinals Logo
Monday, May 25
2:10 PM ET
MLB.TV
Milwaukee Brewers Logo
Jacob Misiorowski Under 17.5 Outs (-116 or Better)
FanDuel Logo

By Derek Carty

THE BAT X is forecasting 16.11 pitching outs for Jacob Misiorowski compared to 18.34 pitching outs implied by the oddsmakers, so I believe there is value on this prop.

If you take the Under, you'd be projected to win 59% of the time, resulting in a 53% ROI.

Based on a $100 wager, the expected value here would be $53.45.

This play is good down to at least -116.

Love THE BAT X? Get all of Carty's sports betting projections at EV Analytics!

Pick: Jacob Misiorowski Under 17.5 Outs (-116 or Better)



Tanner McGrath's Yankees vs Royals Prediction

New York Yankees Logo
Monday, May 25
3:40 PM ET
MLB.TV
Kansas City Royals Logo
Yankees ML (-168 or Better)
FanDuel Logo

By Tanner McGrath

Our own Sean Zerillo projects some value on the Yankees in this Memorial Day matchup.

While the consensus line sits around -155, Zerillo projects the Yankees ML above -180, providing a nearly 4% edge against the market.

As a reminder, you can get all of Zerillo's PRO lines on the MLB projections tab.

I never enjoy fading Michael Wacha, who consistently overperforms (over the past five seasons: 3.39 ERA, 4.28 xERA).

However, I’m fine with fading Wacha against the Yankees, who are always a top-five lineup against right-handed pitching.

Also, Wacha overperforms because of a reliance upon his changeup, and the Yankees crush changeups. They rank third among MLB lineups in xwOBA against the pitch (.323), behind a league-leading 11 home runs and 12% barrel rate.

New York’s rotation is stacked, and Will Warren is just another up-and-coming elite arm. His stuff rocks (109 Stuff+, 2.13 botERA, 22.3% K-BB), which is part of the reason why the Yankees have won eight of his 10 starts this season.

Zerillo says we should bet the Yankees ML at -168 or better.

Pick: Yankees ML (-168 or Better)



Jon Anderson's Diamondbacks vs Giants Best Bet

Arizona Diamondbacks Logo
Monday, May 25
5:05 PM ET
MLB.TV
San Francisco Giants Logo
Under 7.5 (-115 or Better)
FanDuel Logo

By Jon Anderson

Landen Roupp is one of the toughest pitchers to take deep. He's given up just two homers this year, and only one at home. He keeps the ball on the ground, and his stuff moves a lot to make it really tough to square up. Hitters have a .309 xwOBA against him, and he has a decent K% this year at 23%. So I like his chances to survive this Diamondbacks lineup in San Francisco.

Merrill Kelly pitches for the Snakes, and he's really hit a groove. Just five earned runs in his past three starts without a walk in his last two. He shook off the slow start, and that changeup is back to doing real damage.

I don't expect many runs in this one.

Pick: Under 7.5 (-115 or Better)



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