MLB season is heating up, and we have a full 15-game Wednesday slate, starting at 1:35 p.m. ET with Padres vs. Pirates in Pittsburgh.
I've got four MLB Home Run Props and home-run picks from these games: Astros vs. Rockies, Braves vs. Angels and Tigers vs. Twins.
MLB Home Run Props: Grant's HR Picks
| Game | Time (ET) | Pick |
|---|---|---|
  | 3:10 PM | |
  | 4:07 PM | |
| 4:07 PM | |
  | 7:40 PM | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game. | ||
Editor's Note: A home run parlay is not the author's formal recommendation. These home run picks have value as straight bets.
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Astros vs Rockies HR Prop
Christian Walker is off to a great start to the season and is looking like the hitter we've seen in the past.
The Astros first baseman has a ton of pop and already has his three home runs in 12 games.
Rockies starter Michael Lorenzen is an absolute gas can for power, and Coors Field is one of the best ballparks in the league for home runs.
I have the true odds here around +300, making this a great bet.
Pick: Christian Walker Home Run (+390 or Better)
Braves vs Angels Home Run Pick
The Angels' Reid Detmers had a good year out of the bullpen last season, but as a starting pitcher, he's historically been a big plus matchup for power.
The lefty has around neutral splits, allowing above-average homers to both sides of the plate when in the starting rotation in his career.
Atlanta second baseman Ozzie Albies hasn't had a ton of pop the last two seasons, but he's showing his power again in 2026, with three long balls in 12 games, and these odds are far too high.
I have the true odds around +500, making this a great bet.
Pick: Ozzie Albies Home Run (+570 or Better)
Braves vs Angels Home Run Prop
This is one of the few games today with good weather, and the matchup vs. the Braves' Grant Holmes is good.
Holmes has struggled with righty power in his career, giving up a high 1.43 HR/9.
Angels SS Zach Neto picked up right where he left off last season, with four HRs in 12 games.
He's turning into a legit hitter, and given the matchup, these odds are far too high.
I have the true odds around +400, making this another excellent bet.
Pick: Zach Neto Home Run (+470 or Better)
Tigers vs Twins HR Pick
Tigers shortstop Kevin McGonigle has been fantastic this season, and while he still doesn't have a home run yet, he's been hammering the ball and has just gotten unlucky.
The left-handed rookie gets a great matchup vs. the Twins' Bailey Ober, who has allowed a 1.32 HR/9 in his career vs. lefties and grades out as an even better matchup than that.
The weather should be slightly below average, but with the wind blowing out, it's only a small downgrade to power.
I have the true odds for McGonigle around +525.
Pick: Kevin McGonigle Home Run (+610 or Better)
