The Cleveland Guardians host the Toronto Blue Jays on June 24, 2025. First pitch from Progressive Field is scheduled for 6:40 p.m. EDT; the game will be broadcast on SNET.
Read our Blue Jays vs Guardians prediction and MLB pick below.
My Blue Jays vs Guardians Prediction
- Blue Jays vs Guardians Picks: Blue Jays ML (-110 or better)
Blue Jays vs Guardians Odds
| Blue Jays Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +140 | 9 -110o / -110u | -120 |
| Guardians Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -165 | 9 -110o / -110u | +100 |
Sean Zerillo’s Blue Jays vs Guardians Preview
Unfortunately, the Blue Jays have moved out of range for me — I would bet them at -110 or better.
That said, I'd like to discuss the Jays and Guardians in general.
In the preseason, I bet on the Blue Jays' win total to go Over and the Guardians' win total to go Under. My directionally opposed opinions on those teams have only intensified as the season has progressed.
The Blue Jays are a very underrated team, top to bottom. They have a top-two bullpen, a top-five defense and a rock-solid offense. They’re also in their better split on Tuesday against a left-handed starting pitcher,
Throughout the rest of the series, I’m much likelier to be betting on Toronto than I am on Cleveland, so I’d follow me on the Action Network App and keep an eye on the Jays as the series progresses.
Pick: Blue Jays ML (-110 or better)
