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Blue Jays vs Yankees Prediction, Pick, MLB Odds for Friday, August 21

Blue Jays vs Yankees Prediction, Pick, MLB Odds for Friday, August 21 article feature image
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Photo Credit: Erik Williams-Imagn Images
Pictured: Jesus Sanchez in the on-deck circle

The New York Yankees host the Toronto Blue Jays on August 21, 2026. First pitch from Yankee Stadium is scheduled for 7:05 p.m. EDT. The game will be broadcast on SNET.

The Yankees are favored by -233 on the moneyline and by -1.5 on the run line. The Blue Jays are +197 on the moneyline and +1.5 on the run line. The total is set at 7 runs.

Find my MLB picks and Blue Jays vs Yankees prediction below, as well as probable pitchers, weather report, and more.


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Blue Jays vs Yankees Prediction

  • Blue Jays vs Yankees Pick: Jesus Sanchez Over 0.5 Hits (+120, bet365)

My Blue Jays vs Yankees best bet is on Sanchez to record 1+ hits. Make sure to find the best odds by checking our live MLB odds page.


Blue Jays vs Yankees Odds

Blue Jays Logo
August 21, 2026
7:05 p.m. EDT
SNET
Yankees Logo
Blue Jays Odds
SpreadTotalMoneyline
+1.5
+101
7
-120o / -104u
+197
Yankees Odds
SpreadTotalMoneyline
-1.5
-115
7
-120o / -104u
-233
Odds via bet365. Get up-to-the-minute MLB odds here.
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  • Blue Jays vs Yankees moneyline: Blue Jays +197, Yankees -233
  • Blue Jays vs Yankees over/under: 7 (-120o / -104u)
  • Blue Jays vs Yankees spread: Yankees -1.5 (+101 ), Blue Jays +1.5 (-115)

Blue Jays vs Yankees Probable Pitchers

Mason FluhartyStatCam Schlittler
5-1W-L10-6
0.5fWAR (FanGraphs)4.9
3.71 / 2.77ERA / xERA2.19 / 2.93
3.66 / 3.97FIP / xFIP2.59 / 2.84
16.9K-BB%25.7
36.1GB%41.7
.285BABIP.265
106Stuff+113
100Location+104

Blue Jays vs Yankees MLB Betting Preview

Action PRO projects Blue Jays outfielder Jesus Sanchez for 0.78 hits in today's matchup against the Yankees, giving us a solid 8.6% edge against the market when compared to his current prop line of over/under 1.5 hits, which is enough to tag the Over with a B- grade in our system.


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Blue Jays vs Yankees Pick, Betting Analysis

Sanchez comes into this matchup sitting on 64 hits for the season. Multi-hit games have been tricky for him to stack consistently, but putting the ball in play for at least one base hit is a core part of his game.

Our Action PRO model projects him for 0.78 hits today. That figure sits comfortably above the 0.5 line we need. With three to four guaranteed plate appearances in the Blue Jays lineup, he will get plenty of looks to get that one solid contact against Yankee pitching.

That is where the math works in our favor. We do not need Sanchez to have a heroic 3-for-4 night—we just need a single hit. The model shows the market is underpricing his chances to reach base once, making the Over 0.5 hits a high-value play on today's slate.

Pick: Jesus Sanchez Over 0.5 Hits (+120, bet365)


Blue Jays vs Yankees Weather


Get the latest coverage on MLB Weather.


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