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Nationals vs Orioles Prediction, Pick, MLB Odds for Friday, June 26

Nationals vs Orioles Prediction, Pick, MLB Odds for Friday, June 26 article feature image
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Mike Watters-Imagn Images. Pictured: Nationals SP Andrew Alvarez

The Baltimore Orioles host the Washington Nationals on June 26, 2026. First pitch from Oriole Park at Camden Yards is scheduled for 7:05 p.m. ET. The game will be broadcast on NATS.

The Orioles are favored by -142 on the moneyline and by -1.5 on the run line. The Nationals are +120 on the moneyline and +1.5 on the run line. The total is set at 9 runs.

Find my MLB picks and Nationals vs Orioles prediction below, as well as probable pitchers, weather report, and more.


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Nationals vs Orioles Prediction

  • Nationals vs Orioles Pick: Nationals F5 Moneyline (+102)

My Nationals vs Orioles best bet is on Washington to be ahead after five innings. Make sure to find the best odds by checking our live MLB odds page.


Nationals vs Orioles Odds

Nationals Logo
Friday, Jun 26
7:05 p.m. ET
NATS
Orioles Logo
Nationals Odds
SpreadTotalMoneyline
+1.5
-172
9
-108o / -112u
+120
Orioles Odds
SpreadTotalMoneyline
-1.5
+142
9
-108o / -112u
-142
Odds via FanDuel. Get up-to-the-minute MLB odds here.
FanDuel Logo
  • Nationals vs Orioles moneyline: Nationals +120, Orioles -142
  • Nationals vs Orioles over/under: 9 (-108o / -112u)
  • Nationals vs Orioles spread: Nationals +1.5 (-172), Orioles -1.5 (+142)

Nationals vs Orioles Probable Pitchers

Andrew Alvarez (LHP, WAS)StatTrevor Rogers (LHP, BAL)
1-0W-L4-7
0.8fWAR (FanGraphs)1.1
3.34 / 4.29ERA / xERA5.30 / 4.21
2.73 / 2.72FIP / xFIP4.25 / 4.83
18.2K-BB%9.6
56.8GB%35.9
.360BABIP.293
96Stuff+101
107Location+101

Nationals vs Orioles MLB Betting Preview

Editor's Note: This written pick is a transcription from today's episode of the Payoff Pitch Podcast.

I'm going to take the Nationals F5 moneyline at +102. I like them up to about -105.

I've mentioned this before: with their relievers blowing up every game each of the past three days, they just have no whiffs in that bullpen whatsoever.

The Nats relievers get into late-game situations, and teams start being patient against them, forcing them to throw balls. Eventually, they give up that one big hit. And I want no part of the Nationals bullpen, not only with the way things have gone the past three days, but also just the fatigue they've experienced.

I have four of their relievers marked either as fatigued or unavailable today. So it's an already bad bullpen, arguably even worse on Friday's slate.

However, what I do like is Andrew Alvarez. He ranks 36th among my starting pitchers to this point of the season, with an expected FIP at 2.7, SIERA right around 3, Pitching+ at 107, Stuff+ right around league average, and Location+ at 107.

He typically lasts around four innings, maybe four and 1/3. So you may need the bullpen to come in here and get the final two outs of these first five innings, but I do make the Nationals slight favorites here.


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Nationals vs Orioles Pick, Betting Analysis

I project Orioles SP Trevor Rogers about a half-run worse, and he ranks as a below-average starter, whereas I have Alvarez as an above-average starter.

I'm also going to fade Rogers in this matchup at home tonight and take the Nationals F5 up to -105.

Pick: Nationals F5 Moneyline (+102, FanDuel | Play to -105)


Nationals vs Orioles Weather


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About the Author

Sean graduated from the University of Miami and Hofstra University Law School, later passing the New York State Bar Exam in 2014. He shifted from a legal career to sports data and betting, joining the Action Network in 2019 after working as a baseball video scout and in financial regulatory compliance. As a senior writer and betting analyst, Sean provides MLB and MMA projections using proprietary models and contributes to various digital content and podcasts, becoming a leading expert in betting for baseball, MMA, and horse racing.

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