76ers vs. Celtics Odds & Betting Predictions - October 22, 2025

76ers at Celtics

11:30 pm • NBCS-BOS

Philadelphia 76ers

21-15

117

117 - 116

Boston Celtics

24-14

116

MatchupOpenSpreadTotalMoneyline
76ers 21-15	+2.5	+5.5-112	o230.5-108	+166
Celtics 24-14	u225	-5.5-109	u230.5-112	-198

Wednesday 11:30 p.m.

October 22, 2025

TD GardenBoston

Over 229.5-105

1.9u

J.Embiid u33.5 Pts+Rebs-110

0.45u

BOS -4.5-110

3.5

Under 228.5-110

X: PicksOffice

PHI +4.5-110

0.91u

S.Hauser o9.5 Pts-108

J.Embiid Double-Double (Yes)+122

📚Player Profit 🔑 J.Embiid Double-Double +122 (Player Profit) 2u You will not get better odds ROS than this. He may not play 30+ minutes but he can do this in 15 minutes. He almost had a trip dub the last preseason game in 14 minutes…i love this one Code: sirlocks for 10% off when you get funded at https://www.playerprofit.com/

Over 229-105

0.95u

Awfully high for this matchup plus no Tatum

PHI +160

3.2u

📚Player Profit 🔑 Sixers ML +160 (Player Profit) 2u If you didn’t think this was coming, idek what to tell you. I’m not sure i should get my hopes up too much but they are at peak level rn. Embiid looks great and back in shape, Maxey is stud, VJ gonna be a stud, Grimes is a bucket, Oubre is a vibe…just feels like it’s all coming together. Best odds we will get all year, jump on it. Code: sirlocks for 10% off when you get funded at https://www.playerprofit.com/

J.Embiid o33.5 Pts+Rebs-110

0.25u

Tailing @ChicagoFlow

J.Embiid o4.5 Ast-129

J.Embiid o34.5 Pts+Rebs-114

0.75u

@ChicagoFlow ⭐️⭐️ https://myaction.app/e5jJG5lYFXb

J.Embiid o33.5 Pts+Rebs-125

0.45u

NBA Best Bets: 2 Picks for the Late Slate
Action Network Staff•
Oct 22, 2025 UTC
76ers vs Celtics Parlay: +253 SGP for Tonight
Chilly Bets•
Oct 22, 2025 UTC

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NBA Public Betting

Celtics are 3-2 in their last 5 games.
Celtics are 2-3 in their last 5 games against the spread
Celtics are 12-7 in their road games against the spread
The totals have gone OVER in 2 of Celtics' last 5 games
The totals have gone OVER in 9 of Celtics' 19 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Celtics	21-17	9-10	12-7	13-12	8-5
76ers	22-13-1	9-10	13-3-1	13-7	9-6-1

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Celtics	17-21	9-10	8-11	11-14	6-7
76ers	19-17	10-9	9-8	11-9	8-8

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Celtics	24-14	N/A	N/A	17-8	7-6
76ers	21-15	N/A	N/A	16-4	5-11

date	opponent	score	spread	over/under	moneyline
Oct 15th	TOR	W 110-108	-5 L	U 232	BOS -170
Oct 12th	CLE	W 138-107	-7.5 W	O 231.5	BOS -285
Oct 10th	@TOR	L 105-107	-2.5 L	U 229	TOR -148
Oct 9th	@MEM	W 121-103	-4 W	U 232	BOS -160
Jul 20th	ATL	W 101-80	+1 W	U 185.5	BOS -105