The NBA regular season is back in action with a full slate of games on Saturday, with a total of seven matchups on the docket scheduled for today, featuring an excellent nationally televised doubleheader on NBA TV, as Knicks vs Magic takes center stage at 5:00 p.m. ET, followed by Pistons vs Bucks at 8:00 p.m. ET.
Our staff of basketball betting experts dug into the latest odds and identified six NBA picks for tonight's matchups.
Continue below for our NBA picks, odds, props, and predictions for Saturday, November 22.
NBA Picks, Odds, Props, Predictions: Saturday, November 22
| Game | Time (ET) | Pick |
|---|---|---|
  | 5 p.m. | |
  | 1 p.m. | |
  | 8 p.m. | |
  | 7 p.m. | |
  | 8 p.m. | |
  | 10 p.m. | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our NBA Odds page, which automatically surfaces the best lines for every game. | ||
Knicks vs. Magic
I know a lot of folks are going to play the “payback” angle on the Knicks today, but this New York team has been awful on the road this year.
Over the last 10 games, these two teams are in a dead heat when it comes to net rating.
I’ll take the home team and the better defense for the advantage tonight.
Pick: Magic Moneyline (+100)
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Clippers vs. Hornets
By Bet Labs
This NBA system identifies teams that have struggled against the spread but are poised for short term correction after another poor showing.
When a team has been consistently failing to cover and comes off another game where they fell short of expectations, the betting market tends to overadjust, shading lines too heavily against them.
This creates value for disciplined bettors who recognize that spreads often move more on perception than true performance.
Teams in this range are typically being underestimated, especially as the season progresses beyond the early adjustment phase.
In these spots, motivation to respond is high, public sentiment is low, and pricing inefficiencies emerge that favor the side of teams the market has temporarily abandoned.
Pick: Clippers -1.5 (-105)
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Wizards vs. Bulls
By Joe Dellera
Coby White sat last night against the Heat. So, he should have the freshest legs on the Bulls today against the Wizards.
This is a really good matchup for Coby here in a game that's going to be played at a lightning pace.
White's minutes have been consistent and could see a slight uptick here as he ramps up from injury.
The Wizards allow the second most assists per game to their opponents and they have the league’s worst aDRTG.
He's gone over 30 PRA in both games this season, and the shot volume and potential assists have been significant as well.
I'm adding rebounds with his consistent floor over the last few seasons in a strong rebounding matchup too.
Pick: Coby White Over 28.5 Points + Rebounds + Assists (-111)
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Hawks vs. Pelicans
By Bet Labs
This NBA system focuses on early season games where sharp line movement and public bias create value on the under.
When totals drop from open to close despite heavy public action favoring the over, it signals that professional bettors see inflated expectations for scoring.
Early in the season, teams are still finding rhythm, rotations are inconsistent, and defensive energy tends to outpace offensive efficiency.
The market often overestimates early offensive output, while sharp money corrects the number downward.
By siding with this adjustment and fading public optimism, this system captures the predictive edge of informed movement and early season unders that outperform inflated lines.
Pick: Under 230.5 (-110)
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Pistons vs. Bucks
By Bet Labs
This system identifies value on the Under in division games where the total drops despite the public leaning toward the Over (40% or less of bets).
The reverse movement of the line suggests sharp action is backing the Under.
Division familiarity often leads to tighter, lower-scoring games, enhancing the edge.
Pick: Under 222.5 (-110)
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Kings vs. Nuggets
By Bet Labs
The NBA system titled "Fading Tired Home Teams" targets regular season matchups where fatigue and overvaluation intersect to create an edge for visiting teams.
Home teams that have played multiple games in a short span, often three to five within five days, tend to experience a drop in energy and defensive consistency despite the advantage of being on their own court.
The market often overlooks this subtle fatigue effect, assuming comfort at home offsets physical wear, but in reality, quick turnarounds and short rest lead to slower rotations, weaker transition defense, and less efficiency late in games.
Visiting teams facing these tired hosts, particularly when they are more rested and entering the matchup with focus and travel rhythm, tend to outperform expectations against the spread.
This setup consistently rewards bettors who recognize that rest and intensity outweigh location when home favorites are running on fumes.
Pick: Kings +10.5 (-110)
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