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The Minnesota Timberwolves and Miami Heat will square off in the NBA tonight. Tipoff is set for 7:30 p.m. ET from the Kaseya Center in Miami, Florida. The game will broadcast live on ESPN.
The Heat are 1.5-point favorites on the spread over the Timberwolves, with the over/under set at 243.5 total points. The Heat are -120 moneyline favorites to win outright, while the Timberwolves are listed as +102 underdogs to pull off the upset.
Let's get into my Timberwolves vs. Heat predictions and NBA picks for Wednesday, October 21.
Timberwolves vs Heat Prediction
- Timberwolves vs Heat pick: Davion Mitchell Over 8.5 Points (-130)
My Timberwolves vs. Heat best bet is Davion Mitchell to score over 8.5 points, with the best price currently available at FanDuel. Make sure to find the best odds by checking our live NBA odds page.
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Timberwolves vs Heat Odds
- Timberwolves vs Heat spread: Heat -1.5 (-110), Timberwolves +1.5 (-110)
- Timberwolves vs Heat over/under: 243.5 (-110o / -110u)
- Timberwolves vs Heat moneyline: Timberwolves +102, Heat -120
Timberwolves vs Heat NBA Preview
As of the 2026-27 season, Giannis Antetokounmpo and LaMelo Ball are a part of whatever it is we're about to see with Miami and Minnesota — so is Jonathan Kuminga… and Klay Thompson… and Tim Hardaway Jr… and Bobby Portis.
It'll be different, but these are ultimately two teams who really want (and probably expect) to make it to June, even if most onlookers don't have such expectations.
We'll get some key first looks and, more importantly, begin with mostly clean injury reports for Wednesday.
Bam Adebayo (groin), Pelle Larsson (illness) and Dru Smith (calf) all practiced Sunday and Monday, and we expect them to be active — and for the first two to play significant minutes.
For Minnesota, Donte DiVincenzo (Achilles) will miss most of the season.
Timberwolves vs Heat Pick, Betting Analysis
Davion Mitchell is in line for his best season yet, and should outperform this point total before too long.
I think Mitchell averages 12-15 points per game in this system with space to operate alongside Giannis, who will handle the ball and kick out to shooters in this fast Heat offense.
Mitchell made 39.5 percent from three on 3.3 attempts per game last year while fighting for looks with Norman Powell and Tyler Herro, among other now-former Heat players.
This — on paper — is a steal to start the year.
Pick: Davion Mitchell Over 8.5 Points (-130)
