Louisville vs. Indiana Odds & Betting Predictions - December 6, 2025

Louisville at Indiana

7:15 pm • CBS
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Louisville at Indiana Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Louisville
7-1
-5.5
-4.5-105
o161.5-115
-205
Indiana
7-1
u157.5
+4.5-115
u161.5-105
+170
location pinSaturday 7:15 p.m.
December 06, 2025
Gainbridge FieldhouseIndianapolis
Louisville vs. Indiana Expert Picks
Tickle the Twine
Tickle the Twine
Last 30d: 24-23-1 (-1.5u)
Under 162-110
1u

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Prop Odds Comparison

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Line Movement Tracker

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Louisville vs. Indiana Public Betting Percentages

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Louisville

Public

59%

Bets%

41%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Indiana
5-34-21-15-2N/A
Louisville
5-34-21-12-1N/A

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Indiana
4-43-31-14-3N/A
Louisville
4-43-31-12-1N/A

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Indiana
7-1N/AN/A6-1N/A
Louisville
7-1N/AN/A2-1N/A

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Dec 4th@MINNL 64-73---
Nov 29thCOOKW 100-56-O 149.5IND -20000
Nov 26thKSUW 86-69-10.5 WU 164.5IND -562
Nov 20thLINWW 73-53---
Nov 16thIWW 69-61-28.5 LU 157.5-

Louisville vs. Indiana Injury Updates

Louisville Injuries

    Indiana Injuries

    • Tucker DeVries
      F

      DeVries is out for season with upper body

      Out for Season

    Team Stats
    31-65 (48%)
    Field Goals
    29-59 (49%)
    19-26 (73%)
    Free Throws
    17-23 (74%)
    12-35 (34%)
    3P
    10-27 (37%)
    42.38
    Rebounds
    33.5
    19.8
    Assists
    20
    10.25
    Turnovers
    8.88
    8.5
    Steals
    6.88
    3.75
    Blocks
    3.38
    19.88
    Fouls
    17.88

    Louisville vs. Indiana Odds Comparison

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    Louisville at Indiana Team Totals

    MatchupOverUnder
    Louisville
    7-1
    N/A
    N/A
    Indiana
    7-1
    N/A
    N/A