Turn your sports knowledge into winning predictions
21+ or 18+ in Certain Locations. 19+ in ON. Please Play Responsibly. Gambling Problem? Call 1-800-GAMBLER. Visit connexontario.ca or Call 1-866-531-2600 in ON.
No Code Needed

Louisville vs. Indiana Odds & Betting Predictions - December 6, 2025

Louisville at Indiana

7:15 pm • CBS

Louisville Cardinals

13-5
87
87 - 78

Indiana Hoosiers

12-7
78

Louisville at Indiana Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Louisville
13-5
-3.5-110
o162-110
-180
Indiana
12-7
+3.5-110
u162-110
+150
location pinSaturday 7:15 p.m.
December 06, 2025
Gainbridge FieldhouseIndianapolis
Louisville vs. Indiana Expert Picks
Player Prop Savant
Player Prop Savant
Last 30d: 41-59-0 (-20.8u)
Over 160.5-105
1u
Ryan Minion
Ryan Minion
Last 30d: 255-289-3 (-51.6u)
M.Brown o17.5 Pts-130
$1.30
Tickle the Twine
Tickle the Twine
Last 30d: 42-34-1 (+4.0u)
Under 162-110
1u
Ryan Minion
Ryan Minion
Last 30d: 255-289-3 (-51.6u)
LOU -2.5 (1H)-110
$1.00
LOU -4.5-110
$3.00

Louisville vs. Indiana Previews & Analysis

  • Our 4 CBB Best Bets For Saturday article feature image

    Our 4 CBB Best Bets For Saturday

    Action Network Staff•
    Dec 6, 2025 UTC
  • Louisville vs. Indiana: Back More Talented Team article feature image

    Louisville vs. Indiana: Back More Talented Team

    Christian Odjakjian•
    Dec 6, 2025 UTC
  • 2 Spread, O/U Edges Tip at 10 ET article feature image

    2 Spread, O/U Edges Tip at 10 ET

    Alex Kolodziej•
    Dec 6, 2025 UTC
See more NCAAB Coverage Right Arrow

Prop Odds Comparison

Right Arrow
Right Arrow

No props found

Line Movement Tracker

Right Arrow
Right Arrow

Louisville vs. Indiana Public Betting Percentages

Away Logo

Louisville

Public

Home Logo

Indiana

58%

Bets%

42%

Money%

NCAAB Public Betting Right Arrow

Betting Trends

  • Indiana are 1-4 in their last 5 games.
  • Indiana are 2-3 in their last 5 games against the spread
  • Indiana are 3-3 in their road games against the spread
  • The totals have gone OVER in 2 of Indiana' last 5 games
  • The totals have gone OVER in 7 of Indiana' 13 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Indiana		9-106-73-38-51-3
Louisville		10-86-54-37-40-2

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Indiana		9-107-62-48-51-3
Louisville		7-114-73-45-60-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Indiana		12-7N/AN/A10-30-4
Louisville		13-5N/AN/A8-30-2

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Dec 4th@MINNL 64-73-8.5 LU 144.5MINN -463
Nov 29thCOOKW 100-56-29.5 WO 149.5IND -20000
Nov 26thKSUW 86-69-10.5 WU 164.5IND -562
Nov 20thLINWW 73-53-33 LU 155.5-
Nov 16thIWW 69-61-28.5 LU 157.5-

Louisville vs. Indiana Injury Updates

Louisville Injuries

  • Khani Rooths
    F

    Rooths is questionable with illness

    Questionable

  • Mikel Brown
    G

    Brown is out with back

    Out

Indiana Injuries

  • Jason Drake
    G

    Drake is out with foot

    Out

  • Jordan Rayford
    G

    Rayford is out for season with undisclosed

    Out for Season

  • Josh Harris
    F

    Harris is out with foot

    Out

See more NCAAB Injuries Right Arrow
Team Stats

25-54 (46%)
Field Goals
26-63 (41%)
24-28 (86%)
Free Throws
15-19 (79%)
13-31 (42%)
3P
11-34 (32%)
34
Rebounds
27
15
Assists
14
13
Turnovers
12
9
Steals
4
5
Blocks
1
19
Fouls
21

Louisville vs. Indiana Odds Comparison

Right Arrow

Could not load odds

See more NCAAB Odds Right Arrow

Louisville at Indiana Team Totals

MatchupOverUnder
Louisville
13-5
o83.5-120
u83.5-110
Indiana
12-7
o79.5-110
u79.5-120