Michigan State vs. USC Odds, Opening Spread, Start Time for 2023 NCAA Tournament

Michigan State vs. USC Odds

With the men's 2023 NCAA Tournament bracket finally set, March Madness is officially underway.

Find out how 7-seeded Michigan State and 10-seeded USC matchup statistically, plus how our college basketball betting experts are projecting this first-round matchup to play out.

Michigan State vs USC will tip off at 12:15 p.m. ET on Friday, March 17 on CBS.

Statistical Matchup

Instant Analysis

The Trojans have one of the highest “Kill Shot” rates in the nation, as a 10-0 scoring run could spurt at any moment. USC lives in transition in offense, an area the Spartans are 190th in defending.

A bigger problem for Michgian State is a rank of 320th against catch-and-shoot 3-pointers, while USC is 57th nationally in hitting those perimeter shots.

— Collin Wilson

For more coverage of the 2023 NCAA Tournament and Selection Sunday, make sure to check out our experts' live reactions to the bracket reveal and the Selection Sunday live show, where you can get their instant analysis on every matchup as well as some early insights to help you make your bets.

Don't forget to print out your 2023 NCAA Tournament bracket, as well — and while you're there, enter the bet 365 Bracket Challenge content for your chance to win up to $10,000,000. Enter for free at actionnetwork.com/bracket.