NCAA Tournament Odds: Lines, Opening Spread for Every Sweet 16 Game

With March Madness 2023 rolling on, here are the NCAA Tournament odds, lines, opening spread and more for every Sweet 16 game.

As our analysts make their bets and break down their expert picks throughout the week, we'll add their previews and predictions. For now, let's get to the odds and lines.

NCAA Tournament Odds: Lines, Opening Spread for Every Sweet 16 Game of March Madness 2023

Michigan State vs Kansas State Odds, Spread

Kansas State opened as a 1-point favorite over Michigan State in the Sweet 16 of March Madness 2023. Our expert has projected the Michigan State vs Kansas State odds and spread at Michigan State -0.5 for this Sweet 16 March Madness matchup.

No. 7 Michigan State vs No. 3 Kansas State will tip off at 6:30 p.m. ET on Thursday, March 23 on TBS in the East Region.

UConn vs Arkansas Odds, Spread

UConn opened as a 3.5-point favorite over Arkansas in the Sweet 16 of March Madness 2023. Our expert has projected the UConn vs Arkansas odds and spread at UConn -4 for this Sweet 16 March Madness matchup.

No. 4 UConn vs No. 8 Arkansas will tip off at 7:15 p.m. ET on Thursday, March 23 on CBS in the West Region.

Tennessee vs FAU Odds, Spread

Tennessee opened as a 5.5-point favorite over FAUin the Sweet 16 of March Madness 2023. Our expert has projected the Tennessee vs FAU odds and spread at Tennessee -6 for this Sweet 16 March Madness matchup.

No. 4 Tennessee vs No. 9 FAU will tip off at 9 p.m. ET on Thursday, March 23 on TBS in the East Region.

UCLA vs Gonzaga Odds, Opening Spread

UCLA opened as a 1-point favorite over Gonzaga in the Sweet 16 of March Madness 2023. Our expert has projected the UCLA vs Gonzaga odds and spread at a Pick 'Em (PK) for this Sweet 16 March Madness matchup.

UCLA vs Gonzaga will tip off at 9:45 p.m. ET on Thursday, March 23 on CBS in the West Region.

Alabama vs San Diego State Odds, Spread

Alabama opened as a 6-point favorite over San Diego State in the Sweet 16 of March Madness 2023. Our expert has projected the Alabama vs San Diego State odds and spread at Alabama -7.5 for this Sweet 16 March Madness matchup.

No. 1 Alabama vs No. 5 San Diego State will tip off at 6:30 p.m. ET on Friday, March 24 on TBS in the South Region.

Houston vs Miami Odds, Spread

Houston opened as a 7.5-point favorite over Miami in the Sweet 16 of March Madness 2023. Our expert has projected the Miami vs Houston odds and spread at Houston -11 for this Sweet 16 March Madness matchup.

No. 5 Miami vs No. 1 Houston will tip off at 7:15 p.m. ET on Friday, March 24 on CBS in the Midwest Region.

Princeton vs Creighton Odds, Spread

Creighton opened as a 10.5-point favorite over Princeton in the Sweet 16 of March Madness 2023. Our expert has projected the Princeton vs Creighton odds and spread at Creighton -11 for this Sweet 16 March Madness matchup.

No. 15 Princeton vs No. 6 Creighton will tip off at 9 p.m. ET on Friday, March 24 on TBS in the South Region.

Texas vs Xavier Odds, Spread

Texas opened as a 4-point favorite over Xavier in the Sweet 16 of March Madness 2023. Our expert also has projected the Texas vs Xavier odds and spread at Texas -4 for this Sweet 16 March Madness matchup.

No. 2 Texas vs No. 3 Xavier will tip off at 9:45 p.m. ET on Friday, March 24 on CBS in the Midwest Region.