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Iowa vs. USC Odds & Betting Predictions - November 15, 2025

Iowa at USC

8:30 pm • BTN

Iowa Hawkeyes

9-4
21
21 - 26

USC Trojans

9-4
26

Iowa at USC Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Iowa
9-4
+6.5
+6.5-107
o48.5-111
+192
USC
9-4
u49.5
-6.5-114
u48.5-110
-235
location pinSaturday 8:30 p.m.
November 15, 2025
Los Angeles Memorial ColiseumLos Angeles
Iowa vs. USC Expert Picks
Sandy Plashkes
Sandy Plashkes
Last 30d: 130-132-5 (-18.8u)
USC +190 (Live)
1.9u
Picks Office
Picks Office
Last 30d: 197-198-3 (-16.1u)
Under 48.5-105
0.95u
X: PicksOffice for early access
Scott Rickenbach
Scott Rickenbach
Last 30d: 102-91-2 (-1.2u)
USC -6.5-114
1u
Doug Ziefel
Doug Ziefel
Last 30d: 169-205-7 (-8.0u)
J.Lane Anytime TD Scorer Yes+160
0.31u
Vegas Refund
Vegas Refund
Last 30d: 65-55-1 (+4.5u)
USC -6.5-110
1.1u
Ryan Minion
Ryan Minion
Last 30d: 232-240-2 (+49.5u)
USC +380
$3.80
Win Margin ‘1-6’
Collin Wilson
Collin Wilson
Last 30d: 0-0-0 (+0.0u)
Under 49-118
1u
Project 53 but weather conditions worsening with heavy rain and wind gusts in the double digits
Brian Bitler
Brian Bitler
Last 30d: 66-79-2 (-43.5u)
IOWA +6.5-105
2.86u
💰🦡 Jake
💰🦡 Jake
Last 30d: 69-84-1 (-9.6u)
Under 48.5-105
1u
Dan Gaspar
Dan Gaspar
Last 30d: 38-40-0 (-7.3u)
T.Hines o14.5 Rec Yds-115
1.15u
Sandy Plashkes
Sandy Plashkes
Last 30d: 130-132-5 (-18.8u)
USC -6.5-110
1.1u
Cam Is Money
Cam Is Money
Last 30d: 62-51-4 (+2.4u)
USC -6-115
1u
Duck
Duck
Last 30d: 72-87-0 (-10.0u)
USC -6.5-115
1.15u

Iowa vs. USC Previews & Analysis

  • Iowa vs. USC: Who Wins On A Mush Field? article feature image

    Iowa vs. USC: Who Wins On A Mush Field?

    Collin Wilson•
    Nov 15, 2025 UTC
  • Our Parlay for Iowa vs. USC article feature image

    Our Parlay for Iowa vs. USC

    Dead President Picks•
    Nov 15, 2025 UTC
  • Your Week 12 NCAAF Betting Cheat Sheet article feature image

    Your Week 12 NCAAF Betting Cheat Sheet

    Pete Ruden•
    Nov 15, 2025 UTC
See more NCAAF Coverage Right Arrow

Prop Odds Comparison

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No props found

Line Movement Tracker

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Iowa vs. USC Public Betting Percentages

Away Logo

Iowa

Public

Home Logo

USC

41%

Bets%

59%

Money%

NCAAF Public Betting Right Arrow

Betting Trends

  • USC are 4-1 in their last 5 games.
  • USC are 3-2 in their last 5 games against the spread
  • USC are 1-4 in their road games against the spread
  • The totals have gone OVER in 3 of USC' last 5 games
  • The totals have gone OVER in 4 of USC' 7 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
USC		5-74-31-44-61-1
Iowa		9-34-35-04-34-0

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
USC		6-64-32-35-51-1
Iowa		5-73-42-34-30-4

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
USC		9-3N/AN/A9-10-2
Iowa		8-4N/AN/A7-00-4

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Nov 8thNWW 38-17-14.5 WO 54.5USC -662
Nov 1st@NEBW 21-17-4.5 LU 59.5USC -200
Oct 18th@NDL 24-34+10.5 WU 60.5ND +300
Oct 11thMICHW 31-13-3 WU 58.5USC -160
Sep 27th@ILLL 32-34-6.5 LO 62ILL -250
Team Stats

Total

320
Total Yards
360
53
Total Plays
63
6.037735849056604
Yards Per Play
5.714285714285714

Passing

137
YDS
254
13/20
Comps/Atts
23/32
6.85
YPA
7.9375
2/1
TDs/INTs
1/0
0/0
Sacks/Yards
2/13

Rushing

183
Rush Yards
106
33
Attempts
31
5.545454545454546
YPC
3.4193548387096775
1
TDs
2

Turnovers

0
Fumbles Lost
0
1
Interceptions
0

Efficiency

3/3 100%
Redzone
5/5 100%
4/10 0%
3rd Down
5/10 0%
1/2 0%
4th Down
0/1 0%

First Downs

17
Total
21
7
Pass
13
9
Rush
4
1
Penalty
4

Misc

6/70
Penalties/Yards
3/30

Iowa vs. USC Odds Comparison

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Iowa at USC Team Totals

MatchupOverUnder
Iowa
9-4
N/A
N/A
USC
9-4
N/A
N/A