USC vs. Illinois Odds & Betting Predictions - September 27, 2025
USC at Illinois
4:00 pm • FOXUSC at Illinois Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
 USC 6-1 | -1.5 | -6.5-115 | o62-110 | -250 |
 Illinois 3-3 | u56.5 | +6.5-108 | u62-110 | +200 |
Gies Memorial Stadium (Champaign, IL)Champaign
USC vs. Illinois Expert Picks
Collin Wilson
Last 30d: 75-57-2 (+6.8u)
USC +3 (Live)-110
0.5u
ILL +7-115
1u
Coming back live on USC with a slow start
Tyler Shoemaker
Last 30d: 63-83-1 (-18.8u)
Over 58.5-110
5u
Doug Ziefel
Last 30d: 351-390-8 (+13.9u)
Under 61.5-115
0.58u
Jeremiah Rose
Last 30d: 46-47-2 (-0.8u)
ILL +7-115
0.35u
Sandy Plashkes
Last 30d: 98-92-2 (+32.2u)
USC -6.5-115
1.15u
USC +120 (Live)
1u
The Degenerates
Last 30d: 47-47-1 (-2.5u)
ILL +6.5-105
1u
Dan Gaspar
Last 30d: 40-24-0 (+12.8u)
K.Feagin u0.5 Recs+140
1u
VegasIsMyBitch
Last 30d: 0-0-0 (+0.0u)
Over 62-109
0.46u
Mjaybrod
Last 30d: 52-80-1 (-29.4u)
USC -3.5 (Live)-108
1u
Easy bet here
John Feltman
Last 30d: 80-58-0 (+11.0u)
Over 60.5-110
4u
Over 54 (Live)-118
1.69u
Babs .
Last 30d: 44-40-1 (-1.5u)
Under 61.5-115
1u
USC vs. Illinois Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
USC vs. Illinois Public Betting Percentages
Betting Trends
- Illinois are 2-3 in their last 5 games.
- Illinois are 1-4 in their last 5 games against the spread
- Illinois are 1-1 in their road games against the spread
- The totals have gone OVER in 4 of Illinois' last 5 games
- The totals have gone OVER in 3 of Illinois' 4 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Team Stats
364
YDS
331
30/43
Comps/Atts
21/27
8.465116279069768
YPA
12.25925925925926
2/1
TDs/INTs
3/0
1/10
Sacks/Yards
1/8
USC vs. Illinois Odds Comparison
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USC at Illinois Team Totals
MatchupOverUnder | ||
|---|---|---|
USC 6-1 | N/A | N/A |
Illinois 3-3 | N/A | N/A |