Northwestern vs. USC Odds & Betting Predictions - November 8, 2025

Northwestern at USC

2:00 am • FOX

Northwestern Wildcats

@

USC Trojans

MatchupOpenSpreadTotalMoneyline
Northwestern 5-3	N/A	N/A	N/A
USC 5-2	N/A	N/A	N/A

location pin

Saturday 2:00 a.m.

November 08, 2025

Los Angeles Memorial ColiseumLos Angeles

No props found

NCAAF Public Betting

USC are 4-1 in their last 5 games.
USC are 3-2 in their last 5 games against the spread
USC are 1-2 in their road games against the spread
The totals have gone OVER in 3 of USC' last 5 games
The totals have gone OVER in 3 of USC' 4 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
USC	4-3	3-1	1-2	3-3	1-0
Northwestern	5-2-1	4-1	1-1-1	3-1	2-1-1

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
USC	4-3	3-1	1-2	4-2	0-1
Northwestern	2-5-1	1-3-1	1-2	1-2-1	1-3

Straight-Up (ML) History

	overall	home	away	favorite	underdog
USC	5-2	N/A	N/A	5-1	0-1
Northwestern	5-3	N/A	N/A	4-0	1-3

date	opponent	score	spread	over/under	moneyline
Oct 18th	@ND	L 24-34	+10.5 W	U 60.5	ND +300
Oct 11th	MICH	W 31-13	-3 W	U 58.5	USC -160
Sep 27th	@ILL	L 32-34	-6.5 L	O 62	ILL -250
Sep 21st	MSU	W 45-31	-18.5 L	O 55.5	USC -950
Sep 13th	@PUR	W 33-17	-20.5 L	U 59.5	USC -1600

Total

Passing

1379

YDS

2283

127/219

Comps/Atts

158/228

6.3

YPA

10.01

10/9

TDs/INTs

16/4

10/69

Sacks/Yards

6/37

Rushing

1503

Rush Yards

1427

307

Attempts

242

4.9

YPC

5.9

10

TDs

19

Turnovers

Fumbles Lost

9

Interceptions

4

Efficiency

24/27 88.9%

Redzone

33/36 91.7%

52/111 0%

3rd Down

43/81 0%

9/15 0%

4th Down

10/14 0%

First Downs

170

Total

180

64

Pass

98

86

Rush

64

20

Penalty

18

Misc

/

Penalties/Yards

/

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See more NCAAF Odds

MatchupOverUnder
Northwestern 5-3	N/A	N/A
USC 5-2	N/A	N/A