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Northwestern vs. USC Odds & Betting Predictions - November 8, 2025

Northwestern at USC

2:00 am • FOX

Northwestern Wildcats

7-6
17
17 - 38

USC Trojans

9-4
38

Northwestern at USC Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Northwestern
7-6
+16.5
+14.5-112
o54.5-108
+472
USC
9-4
u51.5
-14.5-108
u54.5-111
-662
location pinSaturday 2:00 a.m.
November 08, 2025
Los Angeles Memorial ColiseumLos Angeles
Northwestern vs. USC Expert Picks
John Feltman
John Feltman
Last 30d: 65-69-2 (-12.2u)
USC o33.5 Team Total-125
3u
Dan Gaspar
Dan Gaspar
Last 30d: 0-0-0 (+0.0u)
C.Komolafe o72.5 Rush Yds-114
1u
Picks Office
Picks Office
Last 30d: 180-152-5 (+14.6u)
NW +14.5-110
1u
X: PicksOffice
Collin Wilson
Collin Wilson
Last 30d: 15-10-3 (+5.2u)
USC -14-112
1u
John Feltman
John Feltman
Last 30d: 65-69-2 (-12.2u)
USC o16.5 Team Total (1H)-125
3u
Babs .
Babs .
Last 30d: 41-36-0 (-0.0u)
Over 50.5-118
0.85u
Lines at Lunch
Lines at Lunch
Last 30d: 0-0-0 (+0.0u)
NW +17-130
1.3u
Babs .
Babs .
Last 30d: 41-36-0 (-0.0u)
NW +17-130
1u
💰🦡 Jake
💰🦡 Jake
Last 30d: 74-87-4 (-15.9u)
Under 26.5 (1H)-105
1.58u
Lines at Lunch
Lines at Lunch
Last 30d: 0-0-0 (+0.0u)
Over 51-110
1u
Sandy Plashkes
Sandy Plashkes
Last 30d: 91-96-4 (-14.4u)
Over 51-110
1u
Duck
Duck
Last 30d: 85-70-0 (+5.0u)
NW +14.5-105
1.05u

Northwestern vs. USC Previews & Analysis

  • Northwestern vs. USC: Trojans Will Roll article feature image

    Northwestern vs. USC: Trojans Will Roll

    John Feltman•
    Nov 8, 2025 UTC
  • College Football Week 11 Best Bets & Parlay Picks! | Big Bets On Campus LIVE article feature image

    College Football Week 11 Best Bets & Parlay Picks! | Big Bets On Campus LIVE

    •
    Nov 8, 2025 UTC
  • The Big Bets On Campus Weekend Warmup! | College Football Week 11 article feature image

    The Big Bets On Campus Weekend Warmup! | College Football Week 11

    Joshua Nunn•
    Nov 7, 2025 UTC
  • Our +156 SGP For Northwestern-USC article feature image

    Our +156 SGP For Northwestern-USC

    Dead President Picks•
    Nov 7, 2025 UTC
See more NCAAF Coverage Right Arrow

Prop Odds Comparison

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Line Movement Tracker

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Northwestern vs. USC Public Betting Percentages

Away Logo

Northwestern

Public

Home Logo

USC

48%

Bets%

52%

Money%

NCAAF Public Betting Right Arrow

Betting Trends

  • USC are 4-1 in their last 5 games.
  • USC are 3-2 in their last 5 games against the spread
  • USC are 1-4 in their road games against the spread
  • The totals have gone OVER in 3 of USC' last 5 games
  • The totals have gone OVER in 4 of USC' 7 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
USC		5-74-31-44-61-1
Northwestern		6-4-25-21-2-23-23-2-2

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
USC		6-64-32-35-51-1
Northwestern		5-6-13-3-12-32-2-13-4

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
USC		9-3N/AN/A9-10-2
Northwestern		6-6N/AN/A5-01-6

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Nov 1st@NEBW 21-17-4.5 LU 59.5USC -200
Oct 18th@NDL 24-34+10.5 WU 60.5ND +300
Oct 11thMICHW 31-13-3 WU 58.5USC -160
Sep 27th@ILLL 32-34-6.5 LO 62ILL -250
Sep 21stMSUW 45-31-18.5 LO 55.5USC -950
Team Stats

Total

280
Total Yards
482
55
Total Plays
64
5.090909090909091
Yards Per Play
7.53125

Passing

150
YDS
309
20/30
Comps/Atts
25/34
5
YPA
9.088235294117647
1/0
TDs/INTs
2/1
2/15
Sacks/Yards
1/9

Rushing

130
Rush Yards
173
25
Attempts
30
5.2
YPC
5.766666666666667
1
TDs
3

Turnovers

2
Fumbles Lost
0
0
Interceptions
1

Efficiency

3/3 100%
Redzone
6/6 100%
4/12 0%
3rd Down
6/11 0%
1/2 0%
4th Down
2/2 0%

First Downs

13
Total
24
4
Pass
14
8
Rush
8
1
Penalty
2

Misc

2/26
Penalties/Yards
4/30

Northwestern vs. USC Odds Comparison

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Northwestern at USC Team Totals

MatchupOverUnder
Northwestern
7-6
o19.5-120
u19.5-105
USC
9-4
o34.5-110
u34.5-115