Pittsburgh vs Louisville Odds & Live Scores - November 21, 2026 | The Action Network

Pittsburgh at Louisville

4:00 pm

Pittsburgh Panthers

@

Louisville Cardinals

MatchupOpenSpreadTotalMoneyline
Pittsburgh 5-3	N/A	N/A	N/A
Louisville 4-3	N/A	N/A	N/A

location pin

Saturday 4:00 p.m.

November 21, 2026

L&N Federal Credit Union StadiumLouisville

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NCAAF Public Betting

Louisville are 2-3 in their last 5 games.
Louisville are 2-3 in their last 5 games against the spread
Louisville are 0-2 in their road games against the spread
The totals have gone OVER in 4 of Louisville' last 5 games
The totals have gone OVER in 3 of Louisville' 4 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Louisville	4-3	3-1	0-2	3-3	1-0
Pittsburgh	4-4	3-2	1-2	2-3	1-1

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Louisville	6-1	3-1	2-0	5-1	1-0
Pittsburgh	4-4	1-4	3-0	2-3	2-0

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Louisville	4-3	N/A	N/A	4-2	0-1
Pittsburgh	5-3	N/A	N/A	3-2	1-1

date	opponent	score	spread	over/under	moneyline
Oct 17th	@SYR	W 34-26	-14.5 L	O 56.5	LOU -650
Oct 9th	FSU	W 44-20	-4 W	O 60.5	LOU -190
Oct 3rd	@NCST	L 28-31	-5.5 L	O 56.5	NCST -220
Sep 26th	WF	L 27-30	-11.5 L	U 57.5	WF -450
Sep 19th	SMU	W 41-31	-3 W	O 57.5	LOU -145

Total

Passing

2326

YDS

1887

179/283

Comps/Atts

126/187

8.22

YPA

10.09

20/5

TDs/INTs

11/3

10/66

Sacks/Yards

14/99

Rushing

1228

Rush Yards

1505

278

Attempts

255

4.42

YPC

5.9

11

TDs

25

Turnovers

Fumbles Lost

5

Interceptions

3

Efficiency

25/29 86.2%

Redzone

21/25 84%

43/103 0%

3rd Down

36/80 0%

7/17 0%

4th Down

0/4 0%

First Downs

186

Total

153

102

Pass

71

67

Rush

72

17

Penalty

10

Misc

/

Penalties/Yards

/

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MatchupOverUnder
Pittsburgh 5-3	N/A	N/A
Louisville 4-3	N/A	N/A