SMU vs. Louisville Odds & Betting Predictions - September 19, 2026

SMU at Louisville

7:30 pm • ESPN2
31 - 41

SMU at Louisville Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
SMU
6-1
+1.5
+3-105
o57.5-110
+122
Louisville
4-3
u56.5
-3-110
u57.5-108
-145
location pinSaturday 7:30 p.m.
September 19, 2026
L&N Federal Credit Union StadiumLouisville
SMU vs. Louisville Expert Picks
Vegas Refund
Vegas Refund
Last 30d: 26-38-1 (-16.0u)
LOU -120
1u
Collin Wilson
Collin Wilson
Last 30d: 77-66-2 (+2.1u)
LOU -118
1u
From the Podcast
Mike McNamara
Mike McNamara
Last 30d: 68-56-2 (+3.8u)
LOU -120
0.33u
Tyler Shoemaker
Tyler Shoemaker
Last 30d: 3-4-0 (-0.4u)
SMU +2.5-114
1.14u
SMU +7.5 (Live)-110
1.1u
SMU +101
0.5u
Doug Ziefel
Doug Ziefel
Last 30d: 412-379-11 (+39.2u)
LOU -112
0.5u
K.Brown Anytime TD Scorer Yes+145
0.49u
Ryan Minion
Ryan Minion
Last 30d: 228-232-2 (+4.0u)
LOU -115
$1.00
#ACTION ✍️✍️ https://discord.gg/aXgTWeNHe
LOU -115
$1.00
Collin Whitchurch
Collin Whitchurch
Last 30d: 117-178-4 (-0.9u)
LOU -118
0.5u
The Degenerates
The Degenerates
Last 30d: 62-59-1 (-1.8u)
LOU PK-120
1u
Mike Calabrese
Mike Calabrese
Last 30d: 37-58-0 (-6.9u)
LOU -104 (Live)
1u
Adding to my position
LOU -1-110
1u
Always up to fade SMU on the road. 2-5 ATS dating back to the start of 2025 away from Dallas. Lincoln Kienholz isn’t getting enough hype.
Brian Bitler
Brian Bitler
Last 30d: 72-75-4 (-3.3u)
SMU +1.5-105
3u
RoyalsProps
RoyalsProps
Last 30d: 39-51-2 (-18.5u)
SMU +2.5-112
1.12u
Player Prop Savant
Player Prop Savant
Last 30d: 86-66-0 (+17.7u)
Under 72.5 (Live)+100
1u
Under 72.5 (Live)-112
1u
Topper
Topper
Last 30d: 116-102-4 (+10.1u)
LOU -2.5-105
0.95u
Ranked Contrarian Overall: 178-118-4,60% (ROI:16%) Season:0-1-0,0% (ROI:-100%) #TSA
Mjaybrod
Mjaybrod
Last 30d: 65-71-0 (-9.4u)
SMU +2-107
1u
Jennings on my dih
Adam Kaufman
Adam Kaufman
Last 30d: 348-316-17 (-12.1u)
LOU -118
1u
💰🦡 Jake
💰🦡 Jake
Last 30d: 94-108-1 (+14.1u)
Under 58.5-108
2.16u
Nick Griffith
Last 30d: 56-51-0 (+9.2u)
SMU +110
1u
BBOC Live!
BBOC Live!
Last 30d: 32-28-2 (+5.1u)

SMU vs. Louisville Previews & Analysis

  • SMU vs. Louisville: How to Bet Top-25 Clash article feature image

    SMU vs. Louisville: How to Bet Top-25 Clash

    Ryan Minion•
    Sep 19, 2026 UTC
  • Hinton's +1700 Parlay for Louisville vs SMU article feature image

    Hinton's +1700 Parlay for Louisville vs SMU

    Alex Hinton•
    Sep 19, 2026 UTC
  • Your Week 3 NCAAF Betting Cheat Sheet article feature image

    Your Week 3 NCAAF Betting Cheat Sheet

    Pete Ruden•
    Sep 19, 2026 UTC
  • Our Week 3 NCAAF Underdog Picks article feature image

    Our Week 3 NCAAF Underdog Picks

    Jordan Vanek•
    Sep 18, 2026 UTC
See more NCAAF Coverage Right Arrow

Prop Odds Comparison

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Line Movement Tracker

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SMU vs. Louisville Public Betting Percentages

Away Logo

SMU

Public

57%

Bets%

43%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Louisville
4-33-10-23-31-0
SMU
3-3-13-20-1-13-2-10-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Louisville
6-13-12-05-11-0
SMU
3-42-31-12-41-0

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Louisville
4-3N/AN/A4-20-1
SMU
6-1N/AN/A6-00-1

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 11thVILLW 59-13-38.5 WO 56.5-
Sep 6th@MISSL 38-41+6.5 WO 54.5MISS +200
Dec 23rdTOLW 27-22-12 LO 44.5LOU -492
Nov 29thUKW 41-0+1 WU 45.5-
Nov 22nd@SMUL 6-38+3.5 LU 49.5SMU +154
Team Stats
479
Total Yards
442
80
Total Plays
60
5.9875
Yards Per Play
7.366666666666666
222
YDS
177
24/35
Comps/Atts
14/23
6.3428571428571425
YPA
7.695652173913044
1/2
TDs/INTs
2/0
2/2
Sacks/Yards
0/0
257
Rush Yards
265
45
Attempts
37
5.711111111111111
YPC
7.162162162162162
3
TDs
4

Turnovers

1
Fumbles Lost
0
2
Interceptions
0

Efficiency

3/4 75%
Redzone
2/2 100%
5/14 0%
3rd Down
3/10 0%
3/5 0%
4th Down
0/0 0%

First Downs

27
Total
22
10
Pass
7
12
Rush
12
5
Penalty
3
8/82
Penalties/Yards
11/110

SMU vs. Louisville Odds Comparison

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SMU at Louisville Team Totals

MatchupOverUnder
SMU
6-1
N/A
N/A
Louisville
4-3
N/A
N/A