Wake Forest vs. Louisville Odds & Betting Predictions - September 26, 2026
Wake Forest at Louisville
4:00 pm • ESPNWake Forest at Louisville Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
 Wake Forest 2-1 | +13.5 | +13-110 | o58.5-105 | +380 |
 Louisville 2-1 | u58.5 | -13-112 | u58.5-115 | -525 |
L&N Federal Credit Union StadiumLouisville
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Wake Forest vs. Louisville Expert Picks
Collin Whitchurch
Last 30d: 58-58-3 (+7.7u)
WF +13-110
0.55u
Collin Wilson
Last 30d: 65-38-1 (+18.8u)
WF +13.5-108
1.1u
Project Louisville -12; Wake pass first offense into a Louisville D that’s 122nd D Pass Success Rate. Finishing drives and penalty advantage for Wake. Cardinals D 120th in opponent pass EPA
Prop Odds Comparison
Line Movement Tracker
Wake Forest vs. Louisville Public Betting Percentages
Betting Trends
- Louisville are 2-1 in their last 5 games.
- Louisville are 3-0 in their last 5 games against the spread
- The totals have gone OVER in 3 of Louisville' last 3 games
- The totals have gone OVER in 2 of Louisville' 2 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 3-0 | 2-0 | N/A | 2-0 | 1-0 |
| 1-2 | 1-1 | 0-1 | 0-2 | 1-0 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 3-0 | 2-0 | N/A | 2-0 | 1-0 |
| 2-1 | 1-1 | 1-0 | 2-0 | 0-1 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 2-1 | N/A | N/A | 2-0 | 0-1 |
| 2-1 | N/A | N/A | 2-0 | 0-1 |
Last 5 Matchups
Team Stats
893
YDS
859
67/108
Comps/Atts
53/80
8.27
YPA
10.74
7/1
TDs/INTs
7/0
5/31
Sacks/Yards
3/19
11/13 84.6%
Redzone
11/11 100%
16/38 0%
3rd Down
15/34 0%
4/6 0%
4th Down
0/1 0%
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Penalties/Yards
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Wake Forest vs. Louisville Odds Comparison
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Wake Forest at Louisville Team Totals
MatchupOverUnder | ||
|---|---|---|
Wake Forest 2-1 | N/A | N/A |
Louisville 2-1 | N/A | N/A |