The Arizona Wildcats take on the Arizona State Sun Devils in Tempe, Arizona. Kickoff is set for 9 p.m. ET on FOX.
Arizona is favored by 2 points on the spread with a moneyline of -130. The total is set at 48.5 points.
Here’s my Arizona vs. Arizona State predictions and college football picks for Friday, November 28.
Arizona vs Arizona State Prediction
• Arizona vs. Arizona State Pick: Arizona ML (-125 or better)
My Arizona State vs. Arizona best bet is on the Wildcats to win outright. Find the best line available on our live NCAAF odds page.
Arizona vs Arizona State Odds
| Arizona Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-2 -110 | 48 -110o / -110u | -130 |
| Arizona St Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+2 -110 | 48 -110o / -110u | +110 |
- Arizona vs Arizona St point spread: Arizona -2 (-110), Arizona St +2 (-110)
- Arizona vs Arizona St over/under: 48 (-110o / -110u)
- Arizona vs Arizona St moneyline: Arizona -130, Arizona St +110
Arizona vs Arizona State Preview
Arizona Wildcats Betting Preview: Most Underrated Team in College Football?
Few teams are as hot and as little discussed as Arizona.
The Wildcats have won four straight games since coming off their second bye week, including 52-17 and 41-17 blowouts over Colorado and Baylor, respectively.
Arizona also upset Cincinnati on the road, and it's only two losses since October began came against top-10 BYU (in overtime) and at Houston (by three points).
This is a tough team to beat.
Noah Fifita likely suits up for his final regular-season game as a Wildcat. If he chooses to go to the NFL, it’s unlikely he plays in whichever mid-level bowl Arizona gets selected to, so it may be his final game in Tucson. Fifita only trails Sawyer Robertson (Baylor) and Josh Hoover (TCU) in passing yards in the Big 12, and he has 25 touchdown passes against just five interceptions.
The 2025 rebound for Fifita, who struggled mightily last year, has been phenomenal.
Arizona fields a deep receiving corps that includes reliable targets like Javin Whatley and explosive athletes like Tre Spivey (who, at one point, had seven touchdowns on just 12 touches, but hasn’t seen the end zone in three games).
The run game is just as multiple, with Texas State transfer Ismail Mahdi leading the way with 734 yards and sophomore Kedrick Reescano scoring eight touchdowns.
Top corner Jay'Vion Cole sat out the Baylor game after exiting Week 12 with an injury. It’s unclear whether he returns this week.
Without Cole, Baylor jumped out to an early 14-7 lead thanks to success through the air. But Arizona settled in and held Baylor out of the end zone in the final three quarters. Treydan Stukes has allowed just a 44.3 passer rating when targeted and has two interceptions of his own.
So while Cole may miss time, the other options are strong.
Opponents generate a quality drive on just 35.6% of possessions, the 19th-best mark among defenses nationally. And opposing offenses score just 1.84 points per possession, suitable for a top-35 mark.
It’s a team with a versatile and multiple scoring attack with a quietly excellent defense staring down 9-3 with a win this week.
Arizona State Sun Devils Betting Preview: Roster In Flux
Just one score away from making a run at a College Football Playoff semifinal last year, Arizona State now sits in serious flux.
Star quarterback Sam Leavitt is out for the season with an injury and reportedly is exploring other options in the transfer portal. Head coach Kenny Dillingham is at the center of multiple major coaching searches, including at Florida.
It’s up to Jeff Sims in his last regular-season game in college football to notch one more huge win for Arizona State against its bitter rival.
Despite the outside noise, the Sun Devils are winners of three straight, including a 42-17 blowout over Colorado on the road that got out of hand in the second half.
Sims has transformed ASU into one of the Big 12's strongest rushing attacks. It’s a top-25 unit nationally in EPA per Rush, and only four teams put up more rushing yardage over their last four games than the Sun Devils (256).
Expect the ground game to continue against Arizona, which ranks 117th nationally in Rushing Success Rate allowed.
Star receiver Jordyn Tyson returned from injury last week but was limited to 29 snaps. Fortunately, Arizona State didn’t need Tyson to play a significant role in the win, targeting him just four times for two receptions and 61 yards.
In the finale, Tyson will need to step back into a leading role.
Arizona State’s defense tightens up with its back against the wall. The Sun Devils rank fourth in the Big 12 in red-zone scoring rate (78.8%), but also 56th nationally in quality drive rate allowed.
Part of that success comes from a very active secondary. Keith Abney and Javan Robinson are among the most willing tacklers at corner as you’ll find anywhere in the country. Adrian Wilson has stepped up big in the absence of veteran Xavion Alford, who’s missed most of the season with an injury.
Whether the future sits in flux or not, Dillingham has this team focused on the present.
It was clear the roster’s mind wasn’t elsewhere last week against Colorado as a seven-point road favorite. Sims and the rest of the team are ready to take care of business.
Defending home turf against its rival in Week 14 is Priority No. 1 for ASU.
Arizona vs Arizona State Pick, Betting Analysis
Arizona leads the Territorial Cup, 51-45-1, as these two teams meet for the 99th time (Arizona State vacated two wins).
Each of the last two meetings featured severe one-sided affairs, but this year has the slimmest talent gap since 2018.
The home team hasn’t won this game since 2022.
Arizona continues to fly under the radar in just about every regard – it sits outside both the CFP and AP polls, receiving just 20 votes in the latter. Arizona is 4-1 ATS in its last five outings, failing to cover against Kansas by a half-point, and nearly making it 5-1 when it took BYU to overtime as a slight underdog.
On the other side, Arizona State climbed back into the top 25 despite one of the more underwhelming resumes in the Big 12. It has the marquee upset win over Texas Tech, but few quality wins, and that ugly 42-10 loss to Utah.
But we’re not here to argue flawed rankings.
Arizona is the more undervalued team in the betting market.
It’s a team playing as well as it has all season long. The Wildcats are playing their best football right now, both on offense and defense, and they have a healthier roster.
Without Leavitt, there’s just less to trust about Arizona State.
Arizona has proven more recently than its in-state rival, so I’ll continue to back the Wildcats in what’s essentially a pick ‘em.
Pick: Arizona ML (-125 or Better)
Arizona vs Arizona State Betting Trends
