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Friday College Football Picks Week 1: Virginia Tech vs. Old Dominion & Temple vs. Duke Lead Top Predictions

Friday College Football Picks Week 1: Virginia Tech vs. Old Dominion & Temple vs. Duke Lead Top Predictions article feature image
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Photo by Dylan Buell/Getty Images. Pictured: D’Wan Mathis #18 of the Temple Owls

  • College football's Week 1 slate rolls on with a handful of primetime matchups on Friday, Sept. 2, 2022.
  • While college football is immensely popular among sports bettors, travel ahead of the Labor Day holiday can make it difficult for many to find time to properly handicap Friday's college football slate.
  • Based on our college football picks and predictions, we identify Friday night's smartest Week 1 bets, including Virginia Tech vs. Old Dominion, Western Michigan vs. Michigan State and Temple vs. Duke.

Friday is a big travel day as many hit the road for final holiday weekend of the summer.

It’s also a fun college football day, with five games ranging from 7-10 p.m. ET.

However, because people are working, packing and traveling, handicapping Friday night’s slate can be tough, even for those looking for some college football action.

If you fall into this category, fear not! Because as the Action Network’s Avery Yang would say: “Gotchu.”

Leveraging our PRO Report, which tracks and summarizes five key betting value indicators, here are Friday night’s smartest college football predictions and picks.

College Football Predictions & Picks

*Odds and predictions as of Friday morning

Virginia Tech vs. Old Dominion Prediction

7 p.m. ET | ESPNU

Let’s get started with a classic case of sharps dropping big bucks and moving lines.

The Virginia Tech vs. Old Dominion total opened at 52.5 but now sits at 47.5 after pros steamed the under multiple times.