76ers vs. Knicks Prediction: NBA Opening Night Best Player Props & Picks

The Polymarket promo code (ACTION) works for NBA Opening Night, and this 76ers vs. Knicks prediction rounds up our best NBA player props for the league's marquee tipoff game.

• The 76ers spent the summer rebuilding around Joel Embiid and Tyrese Maxey, headlined by the free-agent signing of LeBron James and the trade for Jaylen Brown, and both stars make their Philadelphia debuts tonight even as the team works through a thin injury report around Adem Bona, Anfernee Simons and Ariel Hukporti.
• The Knicks open their title defense at Madison Square Garden after beating Philadelphia in last season's playoffs, running back a healthy core of Jalen Brunson, OG Anunoby and Karl-Anthony Towns.

Here is our full picks table before we break down every editor's pick from the board of best prediction markets for tonight's matchup.

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Best NBA Player Props for the 76ers vs. Knicks Prediction

Here are our best NBA player props for NBA Opening Night, grouped by points, rebounds and assists. You can also browse the best prediction market apps or the NBA hub for more coverage of tonight's slate, and our NBA markets page and NBA Futures coverage round out everything else on the board this week.

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Points Prop Today – LeBron James

LeBron James makes his Philadelphia debut tonight at 41 years old, and the Sixers are leaning on him as a lead playmaker rather than a pure scorer in this new-look offense.

Even so, a 15.5-point line is a modest bar for a player who averaged 20.9 points a season ago. The Knicks counter with a deep wing rotation, but nobody on New York's roster is built to check James one-on-one for 30-plus minutes.

On the ticket itself, a $100 buy at a 53¢ average price works out to roughly 189 shares, each worth $1 if the contract resolves Yes.

• If James clears 15.5 points: this ticket returns an estimated $188.68.
• If he doesn't: the full $100 stake is lost, since Polymarket contracts settle all-or-nothing.

It's close to a coin flip, but the payout still covers nearly double your stake on a star who should see a heavy offensive workload in his first game in red, white and blue.

Points Prop Today – OG Anunoby

Anunoby enters this season as one of New York's most complete two-way wings, and his role as a secondary scoring option behind Brunson and Towns has only grown since the Knicks' title run.

Philadelphia's new wing rotation around James and Brown is still finding its footing defensively, and Anunoby's size and shooting give him a clean path to his points number even in a game where the ball may not always find him first. A 16.5-point line is a fair number for a player capable of scoring in bunches when his catch-and-shoot look is falling.

A $100 buy at a 53¢ average price is good for roughly 189 shares on this ticket.

• If Anunoby clears 16.5 points: this ticket returns an estimated $188.68.
• If not: the $100 stake is gone entirely.

Another near coin-flip price that still pays back the bulk of a second stake on top of the original $100.

Points Prop Today – Jaylen Brown

Brown reportedly played a role in recruiting James to Philadelphia, and he arrives as a proven high-volume scorer who should slot in as one of the Sixers' first and second options alongside Embiid and Maxey.

A 20.5-point line reflects real star-level scoring expectations, and Brown has cleared that mark regularly throughout his career whenever he's the clear first or second scoring option on his team. New York's defense will likely throw Anunoby's size at Brown for stretches, but the Knicks don't have a true shutdown answer for a wing this physical.

A $100 buy at a 53¢ average price is roughly 189 shares here as well.

• If Brown clears 20.5 points: this ticket returns an estimated $188.68.
• If not: the full $100 stake is a total loss.

Same risk and reward shape as the two picks above, and a reasonable debut number for Philadelphia's new second star.

Points Prop Today – Jalen Brunson

Brunson is coming off a championship run as New York's offensive engine, and a 26.5-point line reflects that go-to-scorer usage on the opening night of a title defense.

Philadelphia's backcourt defense is still adjusting to life without some of its old rotation pieces, and Brunson has made a career out of scoring efficiently against defenses that haven't had a full training camp to gel.

A $100 buy at a 52¢ average price is roughly 192 shares on this ticket.

• If Brunson clears 26.5 points: this ticket returns an estimated $192.31.
• If not: the full $100 stake is lost, since Polymarket contracts settle all-or-nothing.

A near coin-flip price for the reigning champions' franchise point guard on a night the Garden crowd will be loud for him.

Points Prop Today – Tyrese Maxey

Maxey's raw scoring numbers are expected to dip slightly now that James is sharing playmaking duties, which is reflected in a 21.5-point line that's a touch below his recent career norms.

He should still see plenty of open catch-and-shoot looks created by James's gravity, keeping this number very much in play even in a lesser-usage role.

A $100 buy at a 49¢ average price is roughly 204 shares on this ticket.

• If Maxey clears 21.5 points: this ticket returns an estimated $204.08.
• If not: the $100 stake is a total loss.

A longer number than his teammates' props, but the payout reflects the genuine uncertainty around his role in a brand new offense.

Points Prop Today – Joel Embiid

Embiid's workload is always the swing factor on a slate like this, and a 22.5-point line prices in some of that real uncertainty around his minutes even on a night this big.

When healthy and rolling, Embiid remains one of the most unguardable scorers in the league, and New York's frontcourt options haven't shown they can contain him one-on-one in recent playoff history.

A $100 buy at a 48¢ average price works out to roughly 208 shares.

• If Embiid clears 22.5 points: this ticket returns an estimated $208.33.
• If not: the full $100 stake is lost entirely.

The longest price among this board's points props, built for a trader who wants real leverage on Embiid's workload rather than the safer, shorter-priced numbers above.

Rebounds Prop Today – Joel Embiid

Embiid remains Philadelphia's anchor in the middle even with two new stars drawing attention, and a 7.5-rebound line is a modest number for a center of his size whenever he's upright and logging normal minutes.

New York counters with Towns at center, a strong rebounder in his own right, but the Knicks don't have a true rim-protecting backup who can limit Embiid's second-chance opportunities on the glass. Health is the swing factor here, and nothing in this week's injury report flags Embiid as a concern for the opener.

A $100 buy at a 53¢ average price works out to roughly 189 shares.

• If Embiid clears 7.5 rebounds: this ticket returns an estimated $188.68.
• If not: the $100 stake is lost entirely.

A fair number for a star center who should see a full workload in a game this big.

Rebounds Prop Today – Tyrese Maxey

Maxey projects to play more off the ball now that James is handling primary playmaking duties, and that shift often means more time crashing the glass in transition rather than purely setting up teammates.

A 3.5-rebound line is a modest number for a guard who already contributes on the glass in Philadelphia's up-tempo attack.

A $100 buy at a 52¢ average price is roughly 192 shares here too.

• If Maxey clears 3.5 rebounds: this ticket returns an estimated $192.31.
• If not: the $100 stake is a total loss.

A reasonable number for a guard whose role is expanding in a new-look offense.

Assists Prop Today – Jalen Brunson

Brunson is a true dual threat, and with Towns drawing attention inside, the playmaking reads for New York's guards should stay open early in the shot clock.

A 6.5-assist line is attainable for a point guard this ball-dominant, especially in a game both coaching staffs expect to be played at a brisk pace.

A $100 buy at a 52¢ average price works out to roughly 192 shares on this ticket.

• If Brunson clears 6.5 assists: this ticket returns an estimated $192.31.
• If not: the $100 stake is lost entirely.

Another near coin-flip number for New York's primary ball handler on Opening Night.

Assists Prop Today – LeBron James

James has shaped his entire late-career game around setting up teammates like Embiid and Brown rather than chasing scoring totals, and multiple reports out of camp specifically flagged his passing as the piece most likely to reshape this Sixers offense.

A 7.5-assist line is right in line with his career averages, and a crowded frontcourt full of finishers only helps a passer this gifted.

A $100 buy at a 51¢ average price is roughly 196 shares on this ticket.

• If James clears 7.5 assists: this ticket returns an estimated $196.08.
• If not: the full $100 stake is a total loss.

A near coin-flip price on the exact skill James's own teammates expect him to deliver first.

Beyond these ten player props, the full Moneyline, Spread and Total board for tonight's game is live on Polymarket right now too, and it's worth a scan before tipoff given how much uncertainty surrounds two completely reshaped rotations.

76ers vs. Knicks Moneyline, Spread and Total

Before diving into the rest of the player prop board, here's where this 76ers vs. Knicks prediction stands on the base game lines for NBA Opening Night.

The Knicks are favored at 62% to win outright as they open their championship defense at home, with New York also laying 4.5 points on the spread and the total sitting at 231.5 for a pace both rosters should support early in the season.

Points Props for 76ers vs. Knicks

Our full points board below covers every scoring line Polymarket has priced for tonight's NBA Opening Night prediction, listed from the board as it stands right now.

• LeBron James (Points Over 16.5: Yes 57¢): the next line up for a player who should see heavy minutes in his Sixers debut.
• OG Anunoby (Points Over 17.5: Yes 55¢): a slightly higher bar still within reach on a good shooting night for New York's second scoring option.
• Jaylen Brown (Points Over 20.5: Yes 53¢): a star-level number for Philadelphia's newest wing.
• Tyrese Maxey (Points Over 21.5: Yes 49¢): priced a touch below his recent career norms in a crowded new offense.
• Joel Embiid (Points Over 22.5: Yes 48¢): the board's longest scoring price, reflecting his usual workload uncertainty.
• Jalen Brunson (Points Over 25.5: Yes 94¢): a near-lock number for New York's franchise point guard.

Rebounds Props for 76ers vs. Knicks

Here's the full rebounds board as well, covering every player Polymarket has priced on the glass tonight.

• Jalen Brunson (Rebounds Over 3.5: Yes 45¢): a tougher number for a guard whose role leans heavily toward scoring and passing.
• Tyrese Maxey (Rebounds Over 3.5: Yes 52¢): a realistic number as his role expands off the ball.
• OG Anunoby (Rebounds Over 5.5: Yes 46¢): a fair number for a strong, physical wing defender.
• Jaylen Brown (Rebounds Over 5.5: Yes 55¢): a reasonable floor for a bigger wing who should see plenty of minutes.
• LeBron James (Rebounds Over 6.5: Yes 45¢): a tougher number now that he's sharing size with a deeper frontcourt.
• Joel Embiid (Rebounds Over 7.5: Yes 53¢): a modest bar for a center of his size when healthy.

Assists Props for 76ers vs. Knicks

And here's the full assists board, covering every playmaker Polymarket has priced for tonight's NBA Opening Night prediction.

• OG Anunoby (Assists Over 1.5: Yes 60¢): a low bar for a secondary playmaking option.
• Jaylen Brown (Assists Over 3.5: Yes 49¢): a fair number for a scorer who can still find open teammates.
• Tyrese Maxey (Assists Over 4.5: Yes 52¢): a realistic number even as James takes over more lead ball handling.
• Karl-Anthony Towns (Assists Over 4.5: Yes 61¢): a strong number for a center who facilitates from the elbow and the post.
• Jalen Brunson (Assists Over 6.5: Yes 52¢): New York's primary engine, and a fair number for his usual workload.
• LeBron James (Assists Over 7.5: Yes 51¢): right in line with his career passing averages in a new offense built around his vision.

What's Moving the Market for NBA Opening Night

Among our 10 picks, the shortest prices sit at 53 cents: LeBron James and Jaylen Brown in their Philadelphia debuts, OG Anunoby's points line and Joel Embiid's rebounding number.

Jalen Brunson's points and assists props both sit at 52 cents, a reflection of the market's trust in the reigning champion's franchise player.

On the other end, Joel Embiid's points number is the longest price among our picks at 48 cents, which tracks with how often his workload has fluctuated in recent seasons even when he's listed as available.

It's also worth monitoring the injury report through tipoff, since Adem Bona, Anfernee Simons and Ariel Hukporti all carry day-to-day or out tags into tonight's opener, even though none of the six players featured in this 76ers vs. Knicks prediction are currently listed as a concern.

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4. Follow this guide to trading on Polymarket to buy your first "Yes" or "No" contract on tonight's board.

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Final Thoughts: 76ers vs. Knicks Prediction for NBA Opening Night

A completely reshaped Sixers roster heads to Madison Square Garden to open the season against the team that eliminated them from last year's playoffs.

James and Brown both make their Philadelphia debuts, while Brunson and the Knicks counter as the defending champions with continuity on their side and home-court energy behind them. That's our full 76ers vs. Knicks prediction and every best NBA player prop pick we'd make on the Polymarket board tonight.

76ers vs. Knicks Prediction FAQs

Who wins the 76ers vs. Knicks prediction on NBA Opening Night? The Polymarket board favors the Knicks at 62% to win outright at home, with New York also laying 4.5 points on the spread.

What are the best NBA player props for 76ers vs. Knicks? Our top plays lean on the debut scoring numbers for LeBron James, OG Anunoby and Jaylen Brown, plus Joel Embiid's rebounding floor and Jalen Brunson's scoring and playmaking workload.

How do LeBron James and Jaylen Brown debut for the 76ers? Both players join Philadelphia as part of a major offseason overhaul, with James signing as a free agent and Brown arriving via trade, and both are expected to start alongside Joel Embiid and Tyrese Maxey.

What time does 76ers vs. Knicks tip off on NBA Opening Night? Tipoff is scheduled for 7:00 PM ET at Madison Square Garden as the Knicks open their championship defense.

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What is the point total for 76ers vs. Knicks? The total sits at 231.5 points, priced close to even on both the over and the under.

Are there injury concerns for 76ers vs. Knicks? Philadelphia carries day-to-day tags on Adem Bona and Anfernee Simons, plus a season-ending Achilles injury for Ariel Hukporti, though none of the core rotation pieces featured in this prediction are currently affected.

How do Polymarket player prop contracts resolve? Each over/under contract resolves Yes if the named player clears their listed number in that specific game, and No if they don't. Shares bought at a given price pay out $1 each if the contract resolves in your favor, and nothing if it doesn't.