Bills vs. Buccaneers Odds & Betting Predictions - August 23, 2025

Bills at Buccaneers

11:30 pm • NFL+
23 - 19

Bills at Buccaneers Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Bills
5-1
-1.5-110
o37.5-115
-125
Buccaneers
1-5
+1.5-110
u37.5-105
+105
location pinSaturday 11:30 p.m.
August 23, 2025
Raymond James StadiumTampa
Bills vs. Buccaneers Expert Picks
Brian Bitler
Brian Bitler
Last 30d: 68-78-4 (-25.5u)
BUF -2-110
2.73u
JC Cornell
JC Cornell
Last 30d: 0-0-0 (+0.0u)
TB +1-115
3u
Baker gets a few drives. Teddy B dials in.
BUF +1 (2H)-110
3u
TB +1-115
3u

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Bills vs. Buccaneers Props

Prop Projections

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Bills vs. Buccaneers Public Betting Percentages

Away Logo

Bills

Public

33%

Bets%

67%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Buccaneers
1-50-41-10-11-4
Bills
4-22-12-13-21-0

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Buccaneers
3-32-21-11-02-3
Bills
5-12-13-04-11-0

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Buccaneers
1-5N/AN/A0-11-4
Bills
5-1N/AN/A4-11-0

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Aug 16th@PITW 17-14-1.5 WU 36.5TB -120
Aug 9thTENW 29-7+3.5 WO 34.5TB +164
Jan 13thWASL 20-23-3 LU 51.5WAS -160
Jan 5thNOW 27-19-14.5 LO 44.5TB -1151
Dec 29thCARW 48-14-9.5 WO 47.5TB -510

Bills vs. Buccaneers Injury Updates

Bills Injuries

    Buccaneers Injuries

    • Baker Mayfield
      QB

      Mayfield is doubtful with thumb

      Doubtful

    • Sean Tucker
      RB

      Tucker is questionable with quad

      Questionable

    • Jalen McMillan
      WR

      McMillan is out with knee

      Out

    • Emeka Egbuka
      WR

      Egbuka is questionable with unknown

      Questionable

    Team Stats
    375
    Total Yards
    241
    63
    Total Plays
    55
    6
    Yards Per Play
    4.4
    278
    YDS
    200
    25/30
    Comps/Atts
    25/36
    8.438
    YPA
    5.158
    1/0
    TDs/INTs
    2/0
    2/8
    Sacks/Yards
    2/4
    105
    Rush Yards
    45
    31
    Attempts
    17
    3.387
    YPC
    2.647
    1
    TDs
    0
    0
    Fumbles Lost
    1
    0
    Interceptions
    0

    Efficiency

    2/5 40%
    Redzone
    2/3 66.67%
    3/9 0%
    3rd Down
    8/13 0%
    1/1 0%
    4th Down
    0/0 0%

    First Downs

    25
    Total
    18
    14
    Pass
    14
    7
    Rush
    3
    4
    Penalty
    1
    2/10
    Penalties/Yards
    4/31
    35:38
    Possession
    24:22

    Bills vs. Buccaneers Odds Comparison

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    Bills at Buccaneers Team Totals

    MatchupOverUnder
    Bills
    5-1
    N/A
    N/A
    Buccaneers
    1-5
    N/A
    N/A